AUSWIRKUNGEN DER LUFTVERSCHMUTZUNG AUF DIE LUNGENFUNKTION

A. P. Perruchoud; R. J. Phipps; M. Sielczak; W. M. Abraham

AUSWIRKUNGEN DER LUFTVERSCHMUTZUNG AUF DIE LUNGENFUNKTION

Translated title of the contribution: The effects of air pollution on the function of the lungs

A. P. Perruchoud, R. J. Phipps, M. Sielczak, W. M. Abraham

Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The adverse respiratory health effects of air pollution are discussed. Furthermore, the longterm effect of ozone on pulmonary resistance (R(L)), dynamic compliance (C(dyn)), functional residual capacity (FRC), tracheal mucus velocity (TMV) and ciliary beat frequency (CBF) are analyzed. Ozone produces a significant impairment of mucociliary function (10,9 ± 1,0 before, 7,1 ± 1,0 after O₃; p<.05), which is maintained even after the cessation of exposure (6,9 ± 1,2; p <.05). These changes in mucus transport are not associated with primary defect in ciliary motility or changes in lung mechanics. Thus, it is likely that the pathophysiologic changes are mostly occurring in the mucus secreting structures and this model is one of simple, non-obstructive bronchitis.

Translated title of the contribution	The effects of air pollution on the function of the lungs
Original language	German
Pages (from-to)	126-131
Number of pages	6
Journal	Therapeutische Umschau
Volume	42
Issue number	5
State	Published - Dec 1 1985

ASJC Scopus subject areas

Medicine(all)

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title = "AUSWIRKUNGEN DER LUFTVERSCHMUTZUNG AUF DIE LUNGENFUNKTION",

abstract = "The adverse respiratory health effects of air pollution are discussed. Furthermore, the longterm effect of ozone on pulmonary resistance (R(L)), dynamic compliance (C(dyn)), functional residual capacity (FRC), tracheal mucus velocity (TMV) and ciliary beat frequency (CBF) are analyzed. Ozone produces a significant impairment of mucociliary function (10,9 ± 1,0 before, 7,1 ± 1,0 after O3; p<.05), which is maintained even after the cessation of exposure (6,9 ± 1,2; p <.05). These changes in mucus transport are not associated with primary defect in ciliary motility or changes in lung mechanics. Thus, it is likely that the pathophysiologic changes are mostly occurring in the mucus secreting structures and this model is one of simple, non-obstructive bronchitis.",

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AU - Perruchoud, A. P.

AU - Phipps, R. J.

AU - Sielczak, M.

AU - Abraham, W. M.

PY - 1985/12/1

Y1 - 1985/12/1

N2 - The adverse respiratory health effects of air pollution are discussed. Furthermore, the longterm effect of ozone on pulmonary resistance (R(L)), dynamic compliance (C(dyn)), functional residual capacity (FRC), tracheal mucus velocity (TMV) and ciliary beat frequency (CBF) are analyzed. Ozone produces a significant impairment of mucociliary function (10,9 ± 1,0 before, 7,1 ± 1,0 after O3; p<.05), which is maintained even after the cessation of exposure (6,9 ± 1,2; p <.05). These changes in mucus transport are not associated with primary defect in ciliary motility or changes in lung mechanics. Thus, it is likely that the pathophysiologic changes are mostly occurring in the mucus secreting structures and this model is one of simple, non-obstructive bronchitis.

AB - The adverse respiratory health effects of air pollution are discussed. Furthermore, the longterm effect of ozone on pulmonary resistance (R(L)), dynamic compliance (C(dyn)), functional residual capacity (FRC), tracheal mucus velocity (TMV) and ciliary beat frequency (CBF) are analyzed. Ozone produces a significant impairment of mucociliary function (10,9 ± 1,0 before, 7,1 ± 1,0 after O3; p<.05), which is maintained even after the cessation of exposure (6,9 ± 1,2; p <.05). These changes in mucus transport are not associated with primary defect in ciliary motility or changes in lung mechanics. Thus, it is likely that the pathophysiologic changes are mostly occurring in the mucus secreting structures and this model is one of simple, non-obstructive bronchitis.

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ER -

AUSWIRKUNGEN DER LUFTVERSCHMUTZUNG AUF DIE LUNGENFUNKTION

Abstract

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