Translated title of the contribution: The effects of air pollution on the function of the lungs

A. P. Perruchoud, R. J. Phipps, M. Sielczak, W. M. Abraham

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The adverse respiratory health effects of air pollution are discussed. Furthermore, the longterm effect of ozone on pulmonary resistance (R(L)), dynamic compliance (C(dyn)), functional residual capacity (FRC), tracheal mucus velocity (TMV) and ciliary beat frequency (CBF) are analyzed. Ozone produces a significant impairment of mucociliary function (10,9 ± 1,0 before, 7,1 ± 1,0 after O3; p<.05), which is maintained even after the cessation of exposure (6,9 ± 1,2; p <.05). These changes in mucus transport are not associated with primary defect in ciliary motility or changes in lung mechanics. Thus, it is likely that the pathophysiologic changes are mostly occurring in the mucus secreting structures and this model is one of simple, non-obstructive bronchitis.

Translated title of the contributionThe effects of air pollution on the function of the lungs
Original languageGerman
Pages (from-to)126-131
Number of pages6
JournalTherapeutische Umschau
Issue number5
StatePublished - Dec 1 1985

ASJC Scopus subject areas

  • Medicine(all)


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