The effect of tocopheryl phosphates on atherosclerosis progression in rabbits fed with a high cholesterol diet

Yesim Negis, Nurgül Aytan, Nesrin Özer, Esra Ogru, Roksan Libinaki, Robert Gianello, Angelo Azzi, Jean Marc Zingg

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

The effect of tocopheryl phosphate on atherosclerosis progression has been studied in rabbits, fed with a 2% cholesterol diet and compared with an equivalent amount of α-tocopheryl acetate. The results show that the atherosclerotic-preventing effect of the phosphate derivative was more pronounced than that of the acetate derivative. α-Tocopheryl phosphate was also more potent in diminishing the expression of CD36 than the acetate derivative.

Original languageEnglish (US)
Pages (from-to)63-66
Number of pages4
JournalArchives of Biochemistry and Biophysics
Volume450
Issue number1
DOIs
StatePublished - Jun 1 2006
Externally publishedYes

Keywords

  • Antioxidants
  • Atherosclerosis
  • Tocopherol
  • Tocopheryl phosphate

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology

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