The effect of sympathomimetic drugs on post-lymphadenectomy aspermia

Kenneth G Proctor, S. S. Howards

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A double-blind controlled study of the effect on semen quality of 4 alpha-adrenergic agents with and without antihistamines was conducted in a patient who had failure of emission secondary to retroperitoneal lymphadenectomy for testis cancer. No other controlled studies are available. All of the alpha-adrenergic drugs allowed the patient to produce an ejaculate. The effects were similar. The addition of antihistamine did not improve the semen quality. Four days of treatment were consistently more effective than a single dose, especially for sperm motility. A pregnancy resulted. It is concluded that long-term treatment with alpha-adrenergic drugs is indicated in men with failure of emission secondary to retroperitoneal lymphadenectomy.

Original languageEnglish
Pages (from-to)837-838
Number of pages2
JournalJournal of Urology
Volume129
Issue number4
StatePublished - Jan 1 1983
Externally publishedYes

Fingerprint

Aspermia
Sympathomimetics
Lymph Node Excision
Adrenergic Agents
Semen Analysis
Histamine Antagonists
Sperm Motility
Testicular Neoplasms
Double-Blind Method
Pregnancy
Therapeutics

ASJC Scopus subject areas

  • Urology

Cite this

The effect of sympathomimetic drugs on post-lymphadenectomy aspermia. / Proctor, Kenneth G; Howards, S. S.

In: Journal of Urology, Vol. 129, No. 4, 01.01.1983, p. 837-838.

Research output: Contribution to journalArticle

@article{05820eecaaa445beafe72d1c264c3f5e,
title = "The effect of sympathomimetic drugs on post-lymphadenectomy aspermia",
abstract = "A double-blind controlled study of the effect on semen quality of 4 alpha-adrenergic agents with and without antihistamines was conducted in a patient who had failure of emission secondary to retroperitoneal lymphadenectomy for testis cancer. No other controlled studies are available. All of the alpha-adrenergic drugs allowed the patient to produce an ejaculate. The effects were similar. The addition of antihistamine did not improve the semen quality. Four days of treatment were consistently more effective than a single dose, especially for sperm motility. A pregnancy resulted. It is concluded that long-term treatment with alpha-adrenergic drugs is indicated in men with failure of emission secondary to retroperitoneal lymphadenectomy.",
author = "Proctor, {Kenneth G} and Howards, {S. S.}",
year = "1983",
month = "1",
day = "1",
language = "English",
volume = "129",
pages = "837--838",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - The effect of sympathomimetic drugs on post-lymphadenectomy aspermia

AU - Proctor, Kenneth G

AU - Howards, S. S.

PY - 1983/1/1

Y1 - 1983/1/1

N2 - A double-blind controlled study of the effect on semen quality of 4 alpha-adrenergic agents with and without antihistamines was conducted in a patient who had failure of emission secondary to retroperitoneal lymphadenectomy for testis cancer. No other controlled studies are available. All of the alpha-adrenergic drugs allowed the patient to produce an ejaculate. The effects were similar. The addition of antihistamine did not improve the semen quality. Four days of treatment were consistently more effective than a single dose, especially for sperm motility. A pregnancy resulted. It is concluded that long-term treatment with alpha-adrenergic drugs is indicated in men with failure of emission secondary to retroperitoneal lymphadenectomy.

AB - A double-blind controlled study of the effect on semen quality of 4 alpha-adrenergic agents with and without antihistamines was conducted in a patient who had failure of emission secondary to retroperitoneal lymphadenectomy for testis cancer. No other controlled studies are available. All of the alpha-adrenergic drugs allowed the patient to produce an ejaculate. The effects were similar. The addition of antihistamine did not improve the semen quality. Four days of treatment were consistently more effective than a single dose, especially for sperm motility. A pregnancy resulted. It is concluded that long-term treatment with alpha-adrenergic drugs is indicated in men with failure of emission secondary to retroperitoneal lymphadenectomy.

UR - http://www.scopus.com/inward/record.url?scp=0020529370&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020529370&partnerID=8YFLogxK

M3 - Article

C2 - 6842716

AN - SCOPUS:0020529370

VL - 129

SP - 837

EP - 838

JO - Journal of Urology

JF - Journal of Urology

SN - 0022-5347

IS - 4

ER -