The effect of salicylates upon the ventilatory response to carbon dioxide in patients with pulmonary emphysema and hypercapnia

Philip Samet; Anna Rosenthal; William H. Bernstein

doi:10.1016/0002-9343(58)90310-3

The effect of salicylates upon the ventilatory response to carbon dioxide in patients with pulmonary emphysema and hypercapnia

Philip Samet, Anna Rosenthal, William H. Bernstein

Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Oral acute and prolonged salicylate administration to ten male patients with obstructive pulmonary emphysema and hypercarbia failed to improve the impaired ventilatory response to inhaled carbon dioxide so characteristic of this group of subjects. Ventilatory depression consequent to inhalation of high oxygen gas mixtures was not inhibited, in these patients, by salicylate therapy.

Original language	English (US)
Pages (from-to)	215-224
Number of pages	10
Journal	The American journal of medicine
Volume	24
Issue number	2
DOIs	https://doi.org/10.1016/0002-9343(58)90310-3
State	Published - Feb 1958

ASJC Scopus subject areas

Medicine(all)

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title = "The effect of salicylates upon the ventilatory response to carbon dioxide in patients with pulmonary emphysema and hypercapnia",

abstract = "Oral acute and prolonged salicylate administration to ten male patients with obstructive pulmonary emphysema and hypercarbia failed to improve the impaired ventilatory response to inhaled carbon dioxide so characteristic of this group of subjects. Ventilatory depression consequent to inhalation of high oxygen gas mixtures was not inhibited, in these patients, by salicylate therapy.",

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