Abstract
End plate potentials (e.p.p.s) were recorded from frog neuromuscular junctions blocked with high Mg and/or low Ca to characterize the processes underlying increased transmitter release during repetitive stimulation. There was a progressive increase in the amplitude of successive e.p.p.s during repetitive stimulation. Increasing the frequency or duration of stimulation increased this facilitation of e.p.p. amplitudes. Facilitation is defined as the fractional increase in amplitude of a test e.p.p. over a control.
| Original language | English |
|---|---|
| Pages (from-to) | 327-352 |
| Number of pages | 26 |
| Journal | Journal of Physiology |
| Volume | 234 |
| Issue number | 2 |
| State | Published - Dec 1 1973 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Physiology
Cite this
The effect of repetitive stimulation on facilitation of transmitter release at the frog neuromuscular junction. / Magleby, Karl.
In: Journal of Physiology, Vol. 234, No. 2, 01.12.1973, p. 327-352.Research output: Contribution to journal › Article
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TY - JOUR
T1 - The effect of repetitive stimulation on facilitation of transmitter release at the frog neuromuscular junction
AU - Magleby, Karl
PY - 1973/12/1
Y1 - 1973/12/1
N2 - End plate potentials (e.p.p.s) were recorded from frog neuromuscular junctions blocked with high Mg and/or low Ca to characterize the processes underlying increased transmitter release during repetitive stimulation. There was a progressive increase in the amplitude of successive e.p.p.s during repetitive stimulation. Increasing the frequency or duration of stimulation increased this facilitation of e.p.p. amplitudes. Facilitation is defined as the fractional increase in amplitude of a test e.p.p. over a control.
AB - End plate potentials (e.p.p.s) were recorded from frog neuromuscular junctions blocked with high Mg and/or low Ca to characterize the processes underlying increased transmitter release during repetitive stimulation. There was a progressive increase in the amplitude of successive e.p.p.s during repetitive stimulation. Increasing the frequency or duration of stimulation increased this facilitation of e.p.p. amplitudes. Facilitation is defined as the fractional increase in amplitude of a test e.p.p. over a control.
UR - http://www.scopus.com/inward/record.url?scp=0015856913&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0015856913&partnerID=8YFLogxK
M3 - Article
VL - 234
SP - 327
EP - 352
JO - Journal of Physiology
JF - Journal of Physiology
SN - 0022-3751
IS - 2
ER -