The effect of repetitive stimulation on facilitation of transmitter release at the frog neuromuscular junction

Research output: Contribution to journalArticle

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Abstract

End plate potentials (e.p.p.s) were recorded from frog neuromuscular junctions blocked with high Mg and/or low Ca to characterize the processes underlying increased transmitter release during repetitive stimulation. There was a progressive increase in the amplitude of successive e.p.p.s during repetitive stimulation. Increasing the frequency or duration of stimulation increased this facilitation of e.p.p. amplitudes. Facilitation is defined as the fractional increase in amplitude of a test e.p.p. over a control.

Original languageEnglish
Pages (from-to)327-352
Number of pages26
JournalJournal of Physiology
Volume234
Issue number2
StatePublished - Dec 1 1973
Externally publishedYes

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Neuromuscular Junction
Excitatory Postsynaptic Potentials
Anura

ASJC Scopus subject areas

  • Physiology

Cite this

The effect of repetitive stimulation on facilitation of transmitter release at the frog neuromuscular junction. / Magleby, Karl.

In: Journal of Physiology, Vol. 234, No. 2, 01.12.1973, p. 327-352.

Research output: Contribution to journalArticle

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