The effect of radiofrequency hyperthermia and chemotherapy upon human neoplasms when used with adjuvant metronidazole

R. E. Falk, F. L. Moffat, K. Calhoun, Z. Dreznik, L. Makowka, U. Ambus, J. Langer, V. Howard, L. Rotstein, J. A. Falk

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

It appears that metronidazole causes an increase in tumor core temperature above that achieved with RFHT alone, by an as yet undetermined mechanism. Furthermore, radiofrequency hyperthermia, in combination with chemotherapy, can produce objective evidence of tumor repression in 30 to 50% of the patients with metastatic cancer. These results justify proceeding to a randomized prospective trial of RFHT and chemotherapy in specific human neoplasms. Such a study is currently being undertaken at this center.

Original languageEnglish (US)
Pages (from-to)505-512
Number of pages8
JournalSurgery Gynecology and Obstetrics
Volume157
Issue number6
StatePublished - Dec 1 1983
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Obstetrics and Gynecology

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    Falk, R. E., Moffat, F. L., Calhoun, K., Dreznik, Z., Makowka, L., Ambus, U., Langer, J., Howard, V., Rotstein, L., & Falk, J. A. (1983). The effect of radiofrequency hyperthermia and chemotherapy upon human neoplasms when used with adjuvant metronidazole. Surgery Gynecology and Obstetrics, 157(6), 505-512.