TY - JOUR
T1 - The effect of mitomycin C on superficial bladder cancer
AU - Soloway, M. S.
AU - Murphy, W. M.
AU - DeFuria, M. D.
AU - Crooke, S.
AU - Finebaum, P.
PY - 1981/1/1
Y1 - 1981/1/1
N2 - A course of intravesical mitomycin C, consisting of 8 weekly doses of 30 or 40 mg., was evaluated in 16 patients with superficial bladder cancer (stages O and A). Cystoscopically documented tumor was destroyed completely in 11 patients (69 per cent), while 3 patients exhibited partial tumor regression. Two patients had only multifocal, grade 3 carcinoma in situ and both had a complete response with negative biopsies and cytology at the 12-week evaluation. Toxicity was minimal. Further data, including longer followup, are needed to define the potentially promising role of this agent in the over-all management of superficial bladder cancer.
AB - A course of intravesical mitomycin C, consisting of 8 weekly doses of 30 or 40 mg., was evaluated in 16 patients with superficial bladder cancer (stages O and A). Cystoscopically documented tumor was destroyed completely in 11 patients (69 per cent), while 3 patients exhibited partial tumor regression. Two patients had only multifocal, grade 3 carcinoma in situ and both had a complete response with negative biopsies and cytology at the 12-week evaluation. Toxicity was minimal. Further data, including longer followup, are needed to define the potentially promising role of this agent in the over-all management of superficial bladder cancer.
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U2 - 10.1016/S0022-5347(17)55149-6
DO - 10.1016/S0022-5347(17)55149-6
M3 - Article
C2 - 6785454
AN - SCOPUS:0019432928
VL - 125
SP - 646
EP - 648
JO - Scientific Computing and Instrumentation
JF - Scientific Computing and Instrumentation
SN - 1078-8956
IS - 5
ER -
