The effect of intracardiac acetylcholine infusion upon right heart dynamics in patients with rheumatic heart disease studied during exercise

William H. Bernstein, Philip Samet, Robert S. Litwak

Research output: Contribution to journalArticle


Intracardiac infusion of acetylcholine into the right atrium or right ventricle during steady-state exercise in 20 patients with rheumatic heart disease resulted in only minimal alterations in the pressure in the pulmonary artery. The vasodilator effect of acetylcholine on the pulmonary artery under these conditions is minimal and of little or no clinical significance.

Original languageEnglish (US)
Pages (from-to)86-91
Number of pages6
JournalAmerican Heart Journal
Issue number1
StatePublished - Jan 1962


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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