Abstract
Acetylcholine was infused into the right atrium or right ventricle in the course of seventy-nine cardiac catheterizations in sixty-seven patients with rheumatic heart disease with mitral stenosis and/or aortic valve disease. Measurements of pulmonary and systemic arterial pressures and cardiac output were carried out before and during acetylcholine infusion. The data demonstrate a slight pulmonary vasodilator effect of acetylcholine; the magnitude of these changes suggests that acetylcholine offers little promise in the treatment of pulmonary hypertension in patients with mitral stenosis.
| Original language | English |
|---|---|
| Pages (from-to) | 32-42 |
| Number of pages | 11 |
| Journal | The American journal of cardiology |
| Volume | 9 |
| Issue number | 1 |
| State | Published - Jan 1 1962 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
The effect of intracardiac acetylcholine infusion upon right heart dynamics in patients with rheumatic heart disease studied at rest. / Samet, Philip; Bernstein, William H.; Fernandez, Luciano; Victoria, William De.
In: The American journal of cardiology, Vol. 9, No. 1, 01.01.1962, p. 32-42.Research output: Contribution to journal › Article
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TY - JOUR
T1 - The effect of intracardiac acetylcholine infusion upon right heart dynamics in patients with rheumatic heart disease studied at rest
AU - Samet, Philip
AU - Bernstein, William H.
AU - Fernandez, Luciano
AU - Victoria, William De
PY - 1962/1/1
Y1 - 1962/1/1
N2 - Acetylcholine was infused into the right atrium or right ventricle in the course of seventy-nine cardiac catheterizations in sixty-seven patients with rheumatic heart disease with mitral stenosis and/or aortic valve disease. Measurements of pulmonary and systemic arterial pressures and cardiac output were carried out before and during acetylcholine infusion. The data demonstrate a slight pulmonary vasodilator effect of acetylcholine; the magnitude of these changes suggests that acetylcholine offers little promise in the treatment of pulmonary hypertension in patients with mitral stenosis.
AB - Acetylcholine was infused into the right atrium or right ventricle in the course of seventy-nine cardiac catheterizations in sixty-seven patients with rheumatic heart disease with mitral stenosis and/or aortic valve disease. Measurements of pulmonary and systemic arterial pressures and cardiac output were carried out before and during acetylcholine infusion. The data demonstrate a slight pulmonary vasodilator effect of acetylcholine; the magnitude of these changes suggests that acetylcholine offers little promise in the treatment of pulmonary hypertension in patients with mitral stenosis.
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UR - http://www.scopus.com/inward/citedby.url?scp=50549176449&partnerID=8YFLogxK
M3 - Article
C2 - 14496597
AN - SCOPUS:50549176449
VL - 9
SP - 32
EP - 42
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 1
ER -