Efecto de las descargas epileptiformes interictales sobre las funciones cognitivas en niños con epilepsia idiopática

Translated title of the contribution: The effect of interictal epileptiform discharges on cognitive function in children with idiopathic epilepsy

Óscar Papazian, I. Alfonso, V. García-Galarreta

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Introduction. Transient cognitive disorders (CD) in benign rolandic epilepsy (BRE), the most common of idiopathic partial epilepsy (IPE), may be secondary to interictal epileptiform discharges (IED). Objectives. To determine incidence and risk factors for persistent TC in students with IE before, during and after antiepileptic (AE). Patients and methods. Inclusion criteria: 6-12 years old, IPE, controlled for 2 years with AE, and follow-up for 5 years. Evaluations: intelligence (Wechsler-III), learning (Wechsler), academic level (Woodcock-Johnson) and attention/behavior (O'Conners-R). Variables: sex, age of onset, seizure type, interval between first seizure and AE onset, EEG results and AE type. Analysis: chi square. Results. Fourteen children had decreased learning and attention span with impulsivity, hyperactivity, low tolerance and agressivity during remission; 12 (85,71%) with temporal lobe epilepsy: 6 (50%) with IED in the left dominant hemisphere, 2 (16,67%) with IED in the right temporal lobe in left dominant hemisphere children, 2 (16,67%) in both temporal lobes in left dominant hemisphere children and 2 (14,29%) with ERB and IED. MRI were normal. Conclusions. Children with idiopathic temporal lobe epilepsy and IED in the left dominant hemisphere are at higher risk for CD than children with other types of IPE. To control the seizures and to abolish the IED are recommended in an attempt to prevent these cognitive disorders.

Translated title of the contributionThe effect of interictal epileptiform discharges on cognitive function in children with idiopathic epilepsy
Original languageSpanish
Pages (from-to)282-284
Number of pages3
JournalRevista de neurologia
Volume36
Issue number3
DOIs
StatePublished - Feb 1 2003

Keywords

  • Antiepileptic drugs
  • Cognitive disorders
  • Idiopathic partial epilepsy
  • Interictal epileptiform discharges

ASJC Scopus subject areas

  • Clinical Neurology

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