Abstract
Given the unique and clinically ominous pathology associated with pulmonary arterial (PA) hypertension (PH) and its implications for the eventual deterioration of right ventricular function, exercise training (ET) was historically not recommended. More recently, a body of literature demonstrating the safety and efficacy of ET in PH has emerged. The primary focus of this review is to provide a synopsis of current evidence assessing the effects of ET on the PA system in patients with PH. The current body of evidence is relatively small and it is not clear if ET improves PA function or vessel characteristics. Nevertheless, studies have consistently found ET leads to numerous clinically relevant benefits including increased: 1) aerobic capacity, 2) muscle strength, 3) exercise tolerance, and 4) quality of life. Thus, ET, given its clinical benefits, is likely to enjoy increased utilization in patients with PH.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 480-488 |
| Number of pages | 9 |
| Journal | Progress in Cardiovascular Diseases |
| Volume | 57 |
| Issue number | 5 |
| DOIs | |
| State | Published - Mar 1 2015 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
The effect of exercise training on the pulmonary arterial system in patients with pulmonary hypertension. / Arena, Ross; Cahalin, Lawrence P; Borghi-Silva, Audrey; Myers, Jonathan.
In: Progress in Cardiovascular Diseases, Vol. 57, No. 5, 01.03.2015, p. 480-488.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The effect of exercise training on the pulmonary arterial system in patients with pulmonary hypertension
AU - Arena, Ross
AU - Cahalin, Lawrence P
AU - Borghi-Silva, Audrey
AU - Myers, Jonathan
PY - 2015/3/1
Y1 - 2015/3/1
N2 - Given the unique and clinically ominous pathology associated with pulmonary arterial (PA) hypertension (PH) and its implications for the eventual deterioration of right ventricular function, exercise training (ET) was historically not recommended. More recently, a body of literature demonstrating the safety and efficacy of ET in PH has emerged. The primary focus of this review is to provide a synopsis of current evidence assessing the effects of ET on the PA system in patients with PH. The current body of evidence is relatively small and it is not clear if ET improves PA function or vessel characteristics. Nevertheless, studies have consistently found ET leads to numerous clinically relevant benefits including increased: 1) aerobic capacity, 2) muscle strength, 3) exercise tolerance, and 4) quality of life. Thus, ET, given its clinical benefits, is likely to enjoy increased utilization in patients with PH.
AB - Given the unique and clinically ominous pathology associated with pulmonary arterial (PA) hypertension (PH) and its implications for the eventual deterioration of right ventricular function, exercise training (ET) was historically not recommended. More recently, a body of literature demonstrating the safety and efficacy of ET in PH has emerged. The primary focus of this review is to provide a synopsis of current evidence assessing the effects of ET on the PA system in patients with PH. The current body of evidence is relatively small and it is not clear if ET improves PA function or vessel characteristics. Nevertheless, studies have consistently found ET leads to numerous clinically relevant benefits including increased: 1) aerobic capacity, 2) muscle strength, 3) exercise tolerance, and 4) quality of life. Thus, ET, given its clinical benefits, is likely to enjoy increased utilization in patients with PH.
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UR - http://www.scopus.com/inward/citedby.url?scp=84924807013&partnerID=8YFLogxK
U2 - 10.1016/j.pcad.2014.03.008
DO - 10.1016/j.pcad.2014.03.008
M3 - Article
C2 - 25782656
AN - SCOPUS:84924807013
VL - 57
SP - 480
EP - 488
JO - Progress in Cardiovascular Diseases
JF - Progress in Cardiovascular Diseases
SN - 0033-0620
IS - 5
ER -