The effect of chloramphenicol treatment on ferrochelatase activity in dogs

David R. Manyan; Adel A. Yunis

doi:10.1016/0006-291X(70)90172-5

The effect of chloramphenicol treatment on ferrochelatase activity in dogs

David R. Manyan, Adel A. Yunis

Medicine

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Chloramphenicol fed to dogs at a dose of 100 mg/kg/day resulted in a decrease in bone marrow ferrochelatase activity to 5-35% of control levels. Chloramphenicol in concentrations of 25 and 50 μg/ml had no effect on ferrochelatase activity in vitro.

Original language	English (US)
Pages (from-to)	926-931
Number of pages	6
Journal	Biochemical and biophysical research communications
Volume	41
Issue number	4
DOIs	https://doi.org/10.1016/0006-291X(70)90172-5
State	Published - Nov 25 1970

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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title = "The effect of chloramphenicol treatment on ferrochelatase activity in dogs",

abstract = "Chloramphenicol fed to dogs at a dose of 100 mg/kg/day resulted in a decrease in bone marrow ferrochelatase activity to 5-35% of control levels. Chloramphenicol in concentrations of 25 and 50 μg/ml had no effect on ferrochelatase activity in vitro.",

author = "Manyan, {David R.} and Yunis, {Adel A.}",

note = "Funding Information: Acknowledgements. This work was supported Health Service Grants AM 13087-02, AM 09001-06, D. H. Sandberg performed the serum chloramphenicol Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

year = "1970",

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AU - Manyan, David R.

AU - Yunis, Adel A.

N1 - Funding Information: Acknowledgements. This work was supported Health Service Grants AM 13087-02, AM 09001-06, D. H. Sandberg performed the serum chloramphenicol Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 1970/11/25

Y1 - 1970/11/25

N2 - Chloramphenicol fed to dogs at a dose of 100 mg/kg/day resulted in a decrease in bone marrow ferrochelatase activity to 5-35% of control levels. Chloramphenicol in concentrations of 25 and 50 μg/ml had no effect on ferrochelatase activity in vitro.

AB - Chloramphenicol fed to dogs at a dose of 100 mg/kg/day resulted in a decrease in bone marrow ferrochelatase activity to 5-35% of control levels. Chloramphenicol in concentrations of 25 and 50 μg/ml had no effect on ferrochelatase activity in vitro.

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The effect of chloramphenicol treatment on ferrochelatase activity in dogs

Abstract

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