Abstract
1. 1. Carnitine added to mitochondria isolated from human newborn white adipose tissue by a new method enhances oxygen consumption, while deoxycarnitine inhibits it. 2. 2. These effects are not seen in adult tissue. 3. 3. Isolated adipose tissue cells from the newborn can be separated into large and small cells. Mitochondria isolated from the former are insensitive to carnitine, while mitochondria isolated from the small cells show increased oxygen consumption on addition of carnitine. 4. 5. It is suggested that these small cells may produce heat by fatty acid oxidation.
| Original language | English |
|---|---|
| Journal | International Journal of Biochemistry |
| Volume | 5 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 1974 |
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Keywords
- adipose tissue
- carnitine
- mitochondria
- Newborn
ASJC Scopus subject areas
- Biochemistry
Cite this
The effect of carnitine on respiration of mitochondria obtained from newborn and adult human subcutaneous white adipose tissue. / Novak, M.; Hahn, P.; Pardo, V.; Monkus, E.; Alzamora, D.
In: International Journal of Biochemistry, Vol. 5, No. 2, 01.01.1974.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The effect of carnitine on respiration of mitochondria obtained from newborn and adult human subcutaneous white adipose tissue
AU - Novak, M.
AU - Hahn, P.
AU - Pardo, V.
AU - Monkus, E.
AU - Alzamora, D.
PY - 1974/1/1
Y1 - 1974/1/1
N2 - 1. 1. Carnitine added to mitochondria isolated from human newborn white adipose tissue by a new method enhances oxygen consumption, while deoxycarnitine inhibits it. 2. 2. These effects are not seen in adult tissue. 3. 3. Isolated adipose tissue cells from the newborn can be separated into large and small cells. Mitochondria isolated from the former are insensitive to carnitine, while mitochondria isolated from the small cells show increased oxygen consumption on addition of carnitine. 4. 5. It is suggested that these small cells may produce heat by fatty acid oxidation.
AB - 1. 1. Carnitine added to mitochondria isolated from human newborn white adipose tissue by a new method enhances oxygen consumption, while deoxycarnitine inhibits it. 2. 2. These effects are not seen in adult tissue. 3. 3. Isolated adipose tissue cells from the newborn can be separated into large and small cells. Mitochondria isolated from the former are insensitive to carnitine, while mitochondria isolated from the small cells show increased oxygen consumption on addition of carnitine. 4. 5. It is suggested that these small cells may produce heat by fatty acid oxidation.
KW - adipose tissue
KW - carnitine
KW - mitochondria
KW - Newborn
UR - http://www.scopus.com/inward/record.url?scp=49549152097&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=49549152097&partnerID=8YFLogxK
U2 - 10.1016/0020-711X(74)90154-2
DO - 10.1016/0020-711X(74)90154-2
M3 - Article
AN - SCOPUS:49549152097
VL - 5
JO - International Journal of Biochemistry and Cell Biology
JF - International Journal of Biochemistry and Cell Biology
SN - 1357-2725
IS - 2
ER -