The effect of alcohol on serum high density lipoprotein (HDL). A Controlled Experiment

Gary E. Fraser, Joseph T. Anderson, Nedra Foster, Ronald Goldberg, David Jacobs, Henry Blackburn

Research output: Contribution to journalArticle

66 Scopus citations

Abstract

A cross-over study using 11 male subjects and a closely controlled diet, investigated the effect of alcohol on serum high density lipoprotein (HDL) components. Smoking status and body weight remained essentially constant and exercise changes were adjusted for in the analysis. As compared to sucrose, alcohol consumption was associated with a significant elevation in serum apolipoprotein A-I (0.37 mg/dl/g/day of alcohol) with similar effects for serum HDL cholesterol (0.14 mg/dl/g/day of alcohol) and serum apolipoprotein A-II (0.11 mg/dl/g/day of alcohol) achieving borderline levels of statistical significance.

Original languageEnglish (US)
Pages (from-to)275-286
Number of pages12
JournalAtherosclerosis
Volume46
Issue number3
DOIs
StatePublished - Mar 1983
Externally publishedYes

Keywords

  • Alcohol
  • Apolipoproteins
  • Cholesterol
  • Exercise
  • Serum high density lipoprotein

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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