The effect of a structured exercise program on nutrition and fitness outcomes in human immunodeficiency virus-infected children

Tracie L Miller, Gabriel Somarriba, Daniel D. Kinnamon, Geoffrey A. Weinberg, Lawrence B Friedman, Gwendolyn B Scott

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The feasibility and effectiveness of a hospital-based exercise-training program followed by a home-based program for improving fitness, strength, and changes in body composition in children and adolescents with HIV were evaluated. Subjects participated in nonrandomized 24-session, hospital supervised exercise training program followed by an 314unsupervised home-based maintenance program. Outcome measurements included muscular strength/endurance, flexibility, relative peak VO2, body composition, and lipids. Seventeen subjects (eight females) with a median age of 15.0 years (range: 6.0-22.6) and BMI z-score of 0.61 (range: -1.70-2.57) at entry completed the intervention. After 24 training sessions, the median increases in muscular strength were between 8% and 50%, depending on muscle group. The median increases in muscle endurance, relative peak VO2, and lean body mass were 38.7% (95% CI: 12.5-94.7; p=0.006), 3.0ml/kg/min (95% CI: 1.5-6.0; p<0.001), and 4.5% (95% CI: 2.4-6.6; p<0.001), respectively. Twelve children completed the home-based maintenance program. Median changes in these outcomes between completion of the hospital-based intervention and a follow-up after completion of the home-based program were near zero. No adverse events occurred during the intervention. A supervised hospital-based fitness program is feasible, safe, and effective for improving general fitness and strength as well as lean body mass in children with HIV.

Original languageEnglish
Pages (from-to)313-319
Number of pages7
JournalAIDS Research and Human Retroviruses
Volume26
Issue number3
DOIs
StatePublished - Mar 1 2010

Fingerprint

HIV
Exercise
Body Composition
Maintenance
Education
Muscles
Lipids

ASJC Scopus subject areas

  • Immunology
  • Virology
  • Infectious Diseases

Cite this

The effect of a structured exercise program on nutrition and fitness outcomes in human immunodeficiency virus-infected children. / Miller, Tracie L; Somarriba, Gabriel; Kinnamon, Daniel D.; Weinberg, Geoffrey A.; Friedman, Lawrence B; Scott, Gwendolyn B.

In: AIDS Research and Human Retroviruses, Vol. 26, No. 3, 01.03.2010, p. 313-319.

Research output: Contribution to journalArticle

@article{e3db7cf79a0f46788853078d4e5c4ca7,
title = "The effect of a structured exercise program on nutrition and fitness outcomes in human immunodeficiency virus-infected children",
abstract = "The feasibility and effectiveness of a hospital-based exercise-training program followed by a home-based program for improving fitness, strength, and changes in body composition in children and adolescents with HIV were evaluated. Subjects participated in nonrandomized 24-session, hospital supervised exercise training program followed by an 314unsupervised home-based maintenance program. Outcome measurements included muscular strength/endurance, flexibility, relative peak VO2, body composition, and lipids. Seventeen subjects (eight females) with a median age of 15.0 years (range: 6.0-22.6) and BMI z-score of 0.61 (range: -1.70-2.57) at entry completed the intervention. After 24 training sessions, the median increases in muscular strength were between 8{\%} and 50{\%}, depending on muscle group. The median increases in muscle endurance, relative peak VO2, and lean body mass were 38.7{\%} (95{\%} CI: 12.5-94.7; p=0.006), 3.0ml/kg/min (95{\%} CI: 1.5-6.0; p<0.001), and 4.5{\%} (95{\%} CI: 2.4-6.6; p<0.001), respectively. Twelve children completed the home-based maintenance program. Median changes in these outcomes between completion of the hospital-based intervention and a follow-up after completion of the home-based program were near zero. No adverse events occurred during the intervention. A supervised hospital-based fitness program is feasible, safe, and effective for improving general fitness and strength as well as lean body mass in children with HIV.",
author = "Miller, {Tracie L} and Gabriel Somarriba and Kinnamon, {Daniel D.} and Weinberg, {Geoffrey A.} and Friedman, {Lawrence B} and Scott, {Gwendolyn B}",
year = "2010",
month = "3",
day = "1",
doi = "10.1089/aid.2009.0198",
language = "English",
volume = "26",
pages = "313--319",
journal = "AIDS Research and Human Retroviruses",
issn = "0889-2229",
publisher = "Mary Ann Liebert Inc.",
number = "3",

}

TY - JOUR

T1 - The effect of a structured exercise program on nutrition and fitness outcomes in human immunodeficiency virus-infected children

AU - Miller, Tracie L

AU - Somarriba, Gabriel

AU - Kinnamon, Daniel D.

AU - Weinberg, Geoffrey A.

AU - Friedman, Lawrence B

AU - Scott, Gwendolyn B

PY - 2010/3/1

Y1 - 2010/3/1

N2 - The feasibility and effectiveness of a hospital-based exercise-training program followed by a home-based program for improving fitness, strength, and changes in body composition in children and adolescents with HIV were evaluated. Subjects participated in nonrandomized 24-session, hospital supervised exercise training program followed by an 314unsupervised home-based maintenance program. Outcome measurements included muscular strength/endurance, flexibility, relative peak VO2, body composition, and lipids. Seventeen subjects (eight females) with a median age of 15.0 years (range: 6.0-22.6) and BMI z-score of 0.61 (range: -1.70-2.57) at entry completed the intervention. After 24 training sessions, the median increases in muscular strength were between 8% and 50%, depending on muscle group. The median increases in muscle endurance, relative peak VO2, and lean body mass were 38.7% (95% CI: 12.5-94.7; p=0.006), 3.0ml/kg/min (95% CI: 1.5-6.0; p<0.001), and 4.5% (95% CI: 2.4-6.6; p<0.001), respectively. Twelve children completed the home-based maintenance program. Median changes in these outcomes between completion of the hospital-based intervention and a follow-up after completion of the home-based program were near zero. No adverse events occurred during the intervention. A supervised hospital-based fitness program is feasible, safe, and effective for improving general fitness and strength as well as lean body mass in children with HIV.

AB - The feasibility and effectiveness of a hospital-based exercise-training program followed by a home-based program for improving fitness, strength, and changes in body composition in children and adolescents with HIV were evaluated. Subjects participated in nonrandomized 24-session, hospital supervised exercise training program followed by an 314unsupervised home-based maintenance program. Outcome measurements included muscular strength/endurance, flexibility, relative peak VO2, body composition, and lipids. Seventeen subjects (eight females) with a median age of 15.0 years (range: 6.0-22.6) and BMI z-score of 0.61 (range: -1.70-2.57) at entry completed the intervention. After 24 training sessions, the median increases in muscular strength were between 8% and 50%, depending on muscle group. The median increases in muscle endurance, relative peak VO2, and lean body mass were 38.7% (95% CI: 12.5-94.7; p=0.006), 3.0ml/kg/min (95% CI: 1.5-6.0; p<0.001), and 4.5% (95% CI: 2.4-6.6; p<0.001), respectively. Twelve children completed the home-based maintenance program. Median changes in these outcomes between completion of the hospital-based intervention and a follow-up after completion of the home-based program were near zero. No adverse events occurred during the intervention. A supervised hospital-based fitness program is feasible, safe, and effective for improving general fitness and strength as well as lean body mass in children with HIV.

UR - http://www.scopus.com/inward/record.url?scp=77950212908&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950212908&partnerID=8YFLogxK

U2 - 10.1089/aid.2009.0198

DO - 10.1089/aid.2009.0198

M3 - Article

VL - 26

SP - 313

EP - 319

JO - AIDS Research and Human Retroviruses

JF - AIDS Research and Human Retroviruses

SN - 0889-2229

IS - 3

ER -