The dunning r3327 prostate adenocarcinoma in the fischer-copenhagen fi rat: A useful model for immunological studies

A. J. Claflin, E. C. McKinney, M. A. Fletcher

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

The Dunning R3327 tumor sublines in the Fischer-Copenhagen F1 rat provide a spectrum of transplantable prostate adenocarcinomas for the study of host-tumor interactions. The tumor can be transplanted with both fresh and cryopreserved cell suspensions. The F1 rat is an appropriate animal for immunologic studies based on humoral and cellular immune responses. Preliminary evidence of the host-tumor relation in the F1 rat indicates that purified membrane preparations induced a specific cytotoxic population of lymphocytes.

Original languageEnglish (US)
Pages (from-to)105-109
Number of pages5
JournalOncology (Switzerland)
Volume34
Issue number3
DOIs
StatePublished - Jan 1 1977

Keywords

  • Dunning R3327 tumor-Prostate adenocarcinoma-Host-tumor interaction-Purified membrane-cytotoxic lymphocytes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'The dunning r3327 prostate adenocarcinoma in the fischer-copenhagen fi rat: A useful model for immunological studies'. Together they form a unique fingerprint.

  • Cite this