The Dunning R3327 tumor sublines in the Fischer-Copenhagen F1 rat provide a spectrum of transplantable prostate adenocarcinomas for the study of host-tumor interactions. The tumor can be transplanted with both fresh and cryopreserved cell suspensions. The F1 rat is an appropriate animal for immunologic studies based on humoral and cellular immune responses. Preliminary evidence of the host-tumor relation in the F1 rat indicates that purified membrane preparations induced a specific cytotoxic population of lymphocytes.
- Dunning R3327 tumor-Prostate adenocarcinoma-Host-tumor interaction-Purified membrane-cytotoxic lymphocytes
ASJC Scopus subject areas
- Cancer Research