The dunning r3327 prostate adenocarcinoma in the fischer-copenhagen fi rat: A useful model for immunological studies

A. J. Claflin; E. C. McKinney; M. A. Fletcher

doi:10.1159/000225201

The dunning r3327 prostate adenocarcinoma in the fischer-copenhagen fi rat: A useful model for immunological studies

A. J. Claflin, E. C. McKinney, M. A. Fletcher

Medicine

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

The Dunning R3327 tumor sublines in the Fischer-Copenhagen F₁ rat provide a spectrum of transplantable prostate adenocarcinomas for the study of host-tumor interactions. The tumor can be transplanted with both fresh and cryopreserved cell suspensions. The F₁ rat is an appropriate animal for immunologic studies based on humoral and cellular immune responses. Preliminary evidence of the host-tumor relation in the F₁ rat indicates that purified membrane preparations induced a specific cytotoxic population of lymphocytes.

Original language	English (US)
Pages (from-to)	105-109
Number of pages	5
Journal	Oncology (Switzerland)
Volume	34
Issue number	3
DOIs	https://doi.org/10.1159/000225201
State	Published - Jan 1 1977

Keywords

Dunning R3327 tumor-Prostate adenocarcinoma-Host-tumor interaction-Purified membrane-cytotoxic lymphocytes

ASJC Scopus subject areas

Oncology
Cancer Research

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