Abstract
This report describes 20 premature infants who have undergone surgical ligation of a patent ductus arteriosus (PDA), diagnosed solely by physical examination in all but 2 instances. There were no operative deaths. Eleven of these 20 infants had severe associated hyaline membrane disease (HMD) necessitating mechanical ventilatory support from the first or second day of life. Only 3 of these 11 infants (27%) ultimately survived to leave the hospital. In contrast, 8 of 9 premature neonates (89%) with severe congestive heart failure but without HMD were discharged alive. Surgical ligation of the PDA in a premature infant is an appropriate and successful mode of treatment when congestive heart failure is refractory to medical management. Proof is lacking, however, to establish the efficacy of PDA ligation in the premature infant with HMD.
| Original language | English |
|---|---|
| Pages (from-to) | 151-156 |
| Number of pages | 6 |
| Journal | Annals of Thoracic Surgery |
| Volume | 22 |
| Issue number | 2 |
| DOIs | |
| State | Published - Dec 1 1976 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Surgery
Cite this
The ductus debate : ligation in prematurity? / Williams, W. H.; Gelband, H.; Bancalari, Eduardo; Bauer, Charles R; Garcia, O.; Tamer, D.; Kaiser, G. A.
In: Annals of Thoracic Surgery, Vol. 22, No. 2, 01.12.1976, p. 151-156.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The ductus debate
T2 - ligation in prematurity?
AU - Williams, W. H.
AU - Gelband, H.
AU - Bancalari, Eduardo
AU - Bauer, Charles R
AU - Garcia, O.
AU - Tamer, D.
AU - Kaiser, G. A.
PY - 1976/12/1
Y1 - 1976/12/1
N2 - This report describes 20 premature infants who have undergone surgical ligation of a patent ductus arteriosus (PDA), diagnosed solely by physical examination in all but 2 instances. There were no operative deaths. Eleven of these 20 infants had severe associated hyaline membrane disease (HMD) necessitating mechanical ventilatory support from the first or second day of life. Only 3 of these 11 infants (27%) ultimately survived to leave the hospital. In contrast, 8 of 9 premature neonates (89%) with severe congestive heart failure but without HMD were discharged alive. Surgical ligation of the PDA in a premature infant is an appropriate and successful mode of treatment when congestive heart failure is refractory to medical management. Proof is lacking, however, to establish the efficacy of PDA ligation in the premature infant with HMD.
AB - This report describes 20 premature infants who have undergone surgical ligation of a patent ductus arteriosus (PDA), diagnosed solely by physical examination in all but 2 instances. There were no operative deaths. Eleven of these 20 infants had severe associated hyaline membrane disease (HMD) necessitating mechanical ventilatory support from the first or second day of life. Only 3 of these 11 infants (27%) ultimately survived to leave the hospital. In contrast, 8 of 9 premature neonates (89%) with severe congestive heart failure but without HMD were discharged alive. Surgical ligation of the PDA in a premature infant is an appropriate and successful mode of treatment when congestive heart failure is refractory to medical management. Proof is lacking, however, to establish the efficacy of PDA ligation in the premature infant with HMD.
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UR - http://www.scopus.com/inward/citedby.url?scp=0017065930&partnerID=8YFLogxK
U2 - 10.1016/S0003-4975(10)63976-8
DO - 10.1016/S0003-4975(10)63976-8
M3 - Article
VL - 22
SP - 151
EP - 156
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
SN - 0003-4975
IS - 2
ER -