The ductus debate: ligation in prematurity?

W. H. Williams, H. Gelband, Eduardo Bancalari, Charles R Bauer, O. Garcia, D. Tamer, G. A. Kaiser

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This report describes 20 premature infants who have undergone surgical ligation of a patent ductus arteriosus (PDA), diagnosed solely by physical examination in all but 2 instances. There were no operative deaths. Eleven of these 20 infants had severe associated hyaline membrane disease (HMD) necessitating mechanical ventilatory support from the first or second day of life. Only 3 of these 11 infants (27%) ultimately survived to leave the hospital. In contrast, 8 of 9 premature neonates (89%) with severe congestive heart failure but without HMD were discharged alive. Surgical ligation of the PDA in a premature infant is an appropriate and successful mode of treatment when congestive heart failure is refractory to medical management. Proof is lacking, however, to establish the efficacy of PDA ligation in the premature infant with HMD.

Original languageEnglish
Pages (from-to)151-156
Number of pages6
JournalAnnals of Thoracic Surgery
Volume22
Issue number2
DOIs
StatePublished - Dec 1 1976

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Hyaline Membrane Disease
Patent Ductus Arteriosus
Premature Infants
Ligation
Heart Failure
Physical Examination
Newborn Infant
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Williams, W. H., Gelband, H., Bancalari, E., Bauer, C. R., Garcia, O., Tamer, D., & Kaiser, G. A. (1976). The ductus debate: ligation in prematurity? Annals of Thoracic Surgery, 22(2), 151-156. https://doi.org/10.1016/S0003-4975(10)63976-8

The ductus debate : ligation in prematurity? / Williams, W. H.; Gelband, H.; Bancalari, Eduardo; Bauer, Charles R; Garcia, O.; Tamer, D.; Kaiser, G. A.

In: Annals of Thoracic Surgery, Vol. 22, No. 2, 01.12.1976, p. 151-156.

Research output: Contribution to journalArticle

Williams, WH, Gelband, H, Bancalari, E, Bauer, CR, Garcia, O, Tamer, D & Kaiser, GA 1976, 'The ductus debate: ligation in prematurity?', Annals of Thoracic Surgery, vol. 22, no. 2, pp. 151-156. https://doi.org/10.1016/S0003-4975(10)63976-8
Williams WH, Gelband H, Bancalari E, Bauer CR, Garcia O, Tamer D et al. The ductus debate: ligation in prematurity? Annals of Thoracic Surgery. 1976 Dec 1;22(2):151-156. https://doi.org/10.1016/S0003-4975(10)63976-8
Williams, W. H. ; Gelband, H. ; Bancalari, Eduardo ; Bauer, Charles R ; Garcia, O. ; Tamer, D. ; Kaiser, G. A. / The ductus debate : ligation in prematurity?. In: Annals of Thoracic Surgery. 1976 ; Vol. 22, No. 2. pp. 151-156.
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