The authors participated in a double blind study on the effectiveness of chymopapain in the treatment of intervertebral disc disease. Results of the double blind study indicated that chymopapain was no more effective than a placebo. The authors challenge the validity of the double blind study because of timing of result evaluation, possible therapeutic activities of the placebo utilized, and possible insufficient dose of chymopapain.
- Low back pain
ASJC Scopus subject areas
- Orthopedics and Sports Medicine
- Clinical Neurology