The double blind study comparing disease to placebo

An editorial comment

Mark Brown, Robert B. Daroff

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The authors participated in a double blind study on the effectiveness of chymopapain in the treatment of intervertebral disc disease. Results of the double blind study indicated that chymopapain was no more effective than a placebo. The authors challenge the validity of the double blind study because of timing of result evaluation, possible therapeutic activities of the placebo utilized, and possible insufficient dose of chymopapain.

Original languageEnglish (US)
Pages (from-to)233-236
Number of pages4
JournalSpine
Volume2
Issue number3
StatePublished - 1977

Fingerprint

Chymopapain
Double-Blind Method
Placebos
Therapeutics

Keywords

  • Chemonucleolysis
  • Chymopapain
  • Low back pain

ASJC Scopus subject areas

  • Clinical Neurology
  • Orthopedics and Sports Medicine

Cite this

The double blind study comparing disease to placebo : An editorial comment. / Brown, Mark; Daroff, Robert B.

In: Spine, Vol. 2, No. 3, 1977, p. 233-236.

Research output: Contribution to journalArticle

Brown, Mark ; Daroff, Robert B. / The double blind study comparing disease to placebo : An editorial comment. In: Spine. 1977 ; Vol. 2, No. 3. pp. 233-236.
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