Abstract
To determine the value of anterior chamber paracentesis with polymerase chain reaction (PCR) in patients with anterior uveitis. Retrospective observational case series. Bascom Palmer Eye Institute. Fifty-three patients with a diagnosis of anterior uveitis who underwent anterior chamber paracentesis with PCR. Anterior chamber paracentesis with PCR of aqueous fluid. Diagnostic utility and frequency of management change based on anterior chamber paracentesis and PCR. There were 15 of 53 (28%) acute and 35 of 53 (65%) chronic anterior uveitis patients. PCR positivity of herpes simplex virus, cytomegalovirus, varicella zoster virus, and Epstein-Barr virus in our population were 4 of 53 (8%), 1 of 47 (2%), 1 of 35 (3%), and 1 of 18 (6%). Overall, 7 of 53 patients (13%) had a change in management because of PCR results from anterior chamber paracentesis. Four patients encountered paracentesis complications (4/53, 7.5%), 1 with long-term sequelae. Anterior chamber paracentesis with PCR had a relatively low diagnostic utility and resulted in few management changes in patients with suspected infectious anterior uveitis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 781-786 |
| Number of pages | 6 |
| Journal | Unknown Journal |
| Volume | 155 |
| Issue number | 5 |
| State | Published - 2013 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
The diagnostic utility of anterior chamber paracentesis with polymerase chain reaction in anterior uveitis. / Anwar, Zane; Galor, Anat; Albini, Thomas A; Miller, Darlene; Perez Quinones, Victor L; Davis, Janet L.
In: Unknown Journal, Vol. 155, No. 5, 2013, p. 781-786.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The diagnostic utility of anterior chamber paracentesis with polymerase chain reaction in anterior uveitis.
AU - Anwar, Zane
AU - Galor, Anat
AU - Albini, Thomas A
AU - Miller, Darlene
AU - Perez Quinones, Victor L
AU - Davis, Janet L
PY - 2013
Y1 - 2013
N2 - To determine the value of anterior chamber paracentesis with polymerase chain reaction (PCR) in patients with anterior uveitis. Retrospective observational case series. Bascom Palmer Eye Institute. Fifty-three patients with a diagnosis of anterior uveitis who underwent anterior chamber paracentesis with PCR. Anterior chamber paracentesis with PCR of aqueous fluid. Diagnostic utility and frequency of management change based on anterior chamber paracentesis and PCR. There were 15 of 53 (28%) acute and 35 of 53 (65%) chronic anterior uveitis patients. PCR positivity of herpes simplex virus, cytomegalovirus, varicella zoster virus, and Epstein-Barr virus in our population were 4 of 53 (8%), 1 of 47 (2%), 1 of 35 (3%), and 1 of 18 (6%). Overall, 7 of 53 patients (13%) had a change in management because of PCR results from anterior chamber paracentesis. Four patients encountered paracentesis complications (4/53, 7.5%), 1 with long-term sequelae. Anterior chamber paracentesis with PCR had a relatively low diagnostic utility and resulted in few management changes in patients with suspected infectious anterior uveitis.
AB - To determine the value of anterior chamber paracentesis with polymerase chain reaction (PCR) in patients with anterior uveitis. Retrospective observational case series. Bascom Palmer Eye Institute. Fifty-three patients with a diagnosis of anterior uveitis who underwent anterior chamber paracentesis with PCR. Anterior chamber paracentesis with PCR of aqueous fluid. Diagnostic utility and frequency of management change based on anterior chamber paracentesis and PCR. There were 15 of 53 (28%) acute and 35 of 53 (65%) chronic anterior uveitis patients. PCR positivity of herpes simplex virus, cytomegalovirus, varicella zoster virus, and Epstein-Barr virus in our population were 4 of 53 (8%), 1 of 47 (2%), 1 of 35 (3%), and 1 of 18 (6%). Overall, 7 of 53 patients (13%) had a change in management because of PCR results from anterior chamber paracentesis. Four patients encountered paracentesis complications (4/53, 7.5%), 1 with long-term sequelae. Anterior chamber paracentesis with PCR had a relatively low diagnostic utility and resulted in few management changes in patients with suspected infectious anterior uveitis.
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UR - http://www.scopus.com/inward/citedby.url?scp=85027921616&partnerID=8YFLogxK
M3 - Article
C2 - 23415597
AN - SCOPUS:85027921616
VL - 155
SP - 781
EP - 786
JO - Scientific Computing and Instrumentation
JF - Scientific Computing and Instrumentation
SN - 1078-8956
IS - 5
ER -