The diagnostic role of nuclear medicine in the acquired immunodeficiency syndrome

W. I. Ganz, Aldo N Serafini

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

This paper is a review of (a) the pathophysiology of the autoimmune deficiency syndrome (AIDS), and (b) the diagnostic procedures nuclear medicine has to evaluate human immunodeficiency virus related disorders. This article is organized in an organ system approach to AIDS pathology. The application of [67Ga]citrate, 111In-labeled white blood cells, [201TI]chloride, single photon emission computed tomographic and positron emission tomographic brain agents, [99mTc]sulfur colloid and [99mTc]methylene diphosphonate to the pulmonary, nervous, gastrointestinal, dermatologic, musculoskeletal, and renal systems is discussed. These radioisotopes allow earlier diagnosis than routine radiographic studies, and can monitor the effect of therapy on disease activity. In this review an attempt is made to provide clinically useful algorithms to suggest a specific pathogen based on the pattern of radionuclidic uptake.

Original languageEnglish
Pages (from-to)1935-1945
Number of pages11
JournalJournal of Nuclear Medicine
Volume30
Issue number12
StatePublished - Dec 1 1989

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Nuclear Medicine
Acquired Immunodeficiency Syndrome
Technetium Tc 99m Medronate
Musculoskeletal System
Colloids
Photons
Sulfur
Citric Acid
Radioisotopes
Chlorides
Early Diagnosis
Leukocytes
HIV
Electrons
Pathology
Kidney
Lung
Brain
Therapeutics

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

The diagnostic role of nuclear medicine in the acquired immunodeficiency syndrome. / Ganz, W. I.; Serafini, Aldo N.

In: Journal of Nuclear Medicine, Vol. 30, No. 12, 01.12.1989, p. 1935-1945.

Research output: Contribution to journalArticle

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