The degree of blood pressure evaluation and end organ damage with severe hypertension: A case-control study

Arthur M. Fournier, L. J. Hoenig, J. M. Sosenko

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

To investigate the association of blood pressure and end-organ damage in patients with severe hypertension in a case-controlled manner, 26 patients with syndromes of acute end-organ damage and severe hypertension were compared with 25 patients with severe but asymptomatic hypertension for a variety of demographic, clinical, and basic laboratory values. Differences were assessed with the Chi-square test and multiple logistic regression analysis. End-organ damage was significantly associated with a degree of systolic and diastolic blood pressure elevation, a history of hypertensive crisis, serum creatinine, and a history of alcohol use, in multivariate analysis. The relationship to creatinine and a history of hypertensive crisis were not present in univariate analysis. The possible relationships of these factors to the pathophysiology of hypertensive crisis are discussed.

Original languageEnglish (US)
Pages (from-to)367-370
Number of pages4
JournalAmerican Journal of the Medical Sciences
Volume306
Issue number6
DOIs
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Medicine(all)

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