The course of axons through the retina and optic nerve head

R. L. Radius, Douglas Anderson

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

By identifying degenerating axons in tissue specimens from 22 primate eyes, it was possible to demonstrate the normal course of axon fibers. Nerve fiber bundles from a group of retinal ganglion cells travel together with little tendency to disperse laterally. In addition, axons are stratified such that processes from more central ganglion cells are successfully added to the inner strata of the retinal nerve fiber layer. Within and behind the lamina cribrosa, areas of degeneration following retinal photocoagulation were well circumscribed and confined to a group of adjacent axon bundles. This degree of retinotopic organization of axons within the nerve head and retinal fiber layer is believed to be consistent with the premise that isolated lesions within the lamina cribrosa could cause well-organized paracentral scotomas such as those characteristic of early glaucoma.

Original languageEnglish
Pages (from-to)1154-1158
Number of pages5
JournalArchives of Ophthalmology
Volume97
Issue number6
StatePublished - Jan 1 1979

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Optic Disk
Axons
Retina
Nerve Fibers
Scotoma
Retinal Degeneration
Retinal Ganglion Cells
Light Coagulation
Ganglia
Glaucoma
Primates

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Radius, R. L., & Anderson, D. (1979). The course of axons through the retina and optic nerve head. Archives of Ophthalmology, 97(6), 1154-1158.

The course of axons through the retina and optic nerve head. / Radius, R. L.; Anderson, Douglas.

In: Archives of Ophthalmology, Vol. 97, No. 6, 01.01.1979, p. 1154-1158.

Research output: Contribution to journalArticle

Radius, RL & Anderson, D 1979, 'The course of axons through the retina and optic nerve head', Archives of Ophthalmology, vol. 97, no. 6, pp. 1154-1158.
Radius, R. L. ; Anderson, Douglas. / The course of axons through the retina and optic nerve head. In: Archives of Ophthalmology. 1979 ; Vol. 97, No. 6. pp. 1154-1158.
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