The contributions of early adverse experiences and trajectories of respiratory sinus arrhythmia on the development of neurobehavioral disinhibition among children with prenatal substance exposure

Elisabeth Conradt, David Degarmo, Phil Fisher, Beau Abar, Barry M. Lester, Linda L. Lagasse, Seetha Shankaran, Henrietta Bada, Charles R Bauer, Toni M. Whitaker, Jane A. Hammond

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Neurobehavioral disinhibition (ND) is a complex condition reflecting a wide range of problems involving difficulties with emotion regulation and behavior control. Respiratory sinus arrhythmia (RSA) is a physiological correlate of emotion regulation that has been studied in a variety of at-risk populations; however, there are no studies of RSA in children with ND. Data were drawn from a prospective longitudinal study of prenatal substance exposure that included 1,073 participants. Baseline RSA and RSA reactivity to an attention-demanding task were assessed at 3, 4, 5, and 6 years. ND was assessed at ages 8/9, 11, and 13/14 years via behavioral dysregulation and executive dysfunction composite measures. Greater exposure to early adversity was related to less RSA reactivity at 3 years, increases in RSA reactivity from ages 3 to 6 years, and increased behavioral dysregulation from ages 8/9 to 13/14. RSA reactivity was examined as a moderator of the association between early adversity and changes in ND. A significant Early Adversity × RSA Reactivity quadratic interaction revealed that children with decelerations in RSA reactivity exhibited increases in behavioral dysregulation, regardless of their exposure to early adversity. However, greater exposure to early adversity was related to greater increases in behavioral dysregulation, but only if children exhibited accelerations in RSA reactivity from ages 3 to 6 years. The results contribute to our understanding of how interactions across multiple levels of analysis contribute to the development of ND.

Original languageEnglish (US)
Pages (from-to)901-916
Number of pages16
JournalDevelopment and Psychopathology
Volume26
Issue number4
DOIs
StatePublished - Nov 1 2014

Fingerprint

Emotions
Respiratory Sinus Arrhythmia
Behavior Control
Deceleration
Longitudinal Studies
Prospective Studies

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Psychiatry and Mental health

Cite this

The contributions of early adverse experiences and trajectories of respiratory sinus arrhythmia on the development of neurobehavioral disinhibition among children with prenatal substance exposure. / Conradt, Elisabeth; Degarmo, David; Fisher, Phil; Abar, Beau; Lester, Barry M.; Lagasse, Linda L.; Shankaran, Seetha; Bada, Henrietta; Bauer, Charles R; Whitaker, Toni M.; Hammond, Jane A.

In: Development and Psychopathology, Vol. 26, No. 4, 01.11.2014, p. 901-916.

Research output: Contribution to journalArticle

Conradt, Elisabeth ; Degarmo, David ; Fisher, Phil ; Abar, Beau ; Lester, Barry M. ; Lagasse, Linda L. ; Shankaran, Seetha ; Bada, Henrietta ; Bauer, Charles R ; Whitaker, Toni M. ; Hammond, Jane A. / The contributions of early adverse experiences and trajectories of respiratory sinus arrhythmia on the development of neurobehavioral disinhibition among children with prenatal substance exposure. In: Development and Psychopathology. 2014 ; Vol. 26, No. 4. pp. 901-916.
@article{f2a4e8da965a4a3e910d57a698755056,
title = "The contributions of early adverse experiences and trajectories of respiratory sinus arrhythmia on the development of neurobehavioral disinhibition among children with prenatal substance exposure",
abstract = "Neurobehavioral disinhibition (ND) is a complex condition reflecting a wide range of problems involving difficulties with emotion regulation and behavior control. Respiratory sinus arrhythmia (RSA) is a physiological correlate of emotion regulation that has been studied in a variety of at-risk populations; however, there are no studies of RSA in children with ND. Data were drawn from a prospective longitudinal study of prenatal substance exposure that included 1,073 participants. Baseline RSA and RSA reactivity to an attention-demanding task were assessed at 3, 4, 5, and 6 years. ND was assessed at ages 8/9, 11, and 13/14 years via behavioral dysregulation and executive dysfunction composite measures. Greater exposure to early adversity was related to less RSA reactivity at 3 years, increases in RSA reactivity from ages 3 to 6 years, and increased behavioral dysregulation from ages 8/9 to 13/14. RSA reactivity was examined as a moderator of the association between early adversity and changes in ND. A significant Early Adversity × RSA Reactivity quadratic interaction revealed that children with decelerations in RSA reactivity exhibited increases in behavioral dysregulation, regardless of their exposure to early adversity. However, greater exposure to early adversity was related to greater increases in behavioral dysregulation, but only if children exhibited accelerations in RSA reactivity from ages 3 to 6 years. The results contribute to our understanding of how interactions across multiple levels of analysis contribute to the development of ND.",
author = "Elisabeth Conradt and David Degarmo and Phil Fisher and Beau Abar and Lester, {Barry M.} and Lagasse, {Linda L.} and Seetha Shankaran and Henrietta Bada and Bauer, {Charles R} and Whitaker, {Toni M.} and Hammond, {Jane A.}",
year = "2014",
month = "11",
day = "1",
doi = "10.1017/S095457941400056X",
language = "English (US)",
volume = "26",
pages = "901--916",
journal = "Development and Psychopathology",
issn = "0954-5794",
publisher = "Cambridge University Press",
number = "4",

}

TY - JOUR

T1 - The contributions of early adverse experiences and trajectories of respiratory sinus arrhythmia on the development of neurobehavioral disinhibition among children with prenatal substance exposure

AU - Conradt, Elisabeth

AU - Degarmo, David

AU - Fisher, Phil

AU - Abar, Beau

AU - Lester, Barry M.

AU - Lagasse, Linda L.

AU - Shankaran, Seetha

AU - Bada, Henrietta

AU - Bauer, Charles R

AU - Whitaker, Toni M.

AU - Hammond, Jane A.

PY - 2014/11/1

Y1 - 2014/11/1

N2 - Neurobehavioral disinhibition (ND) is a complex condition reflecting a wide range of problems involving difficulties with emotion regulation and behavior control. Respiratory sinus arrhythmia (RSA) is a physiological correlate of emotion regulation that has been studied in a variety of at-risk populations; however, there are no studies of RSA in children with ND. Data were drawn from a prospective longitudinal study of prenatal substance exposure that included 1,073 participants. Baseline RSA and RSA reactivity to an attention-demanding task were assessed at 3, 4, 5, and 6 years. ND was assessed at ages 8/9, 11, and 13/14 years via behavioral dysregulation and executive dysfunction composite measures. Greater exposure to early adversity was related to less RSA reactivity at 3 years, increases in RSA reactivity from ages 3 to 6 years, and increased behavioral dysregulation from ages 8/9 to 13/14. RSA reactivity was examined as a moderator of the association between early adversity and changes in ND. A significant Early Adversity × RSA Reactivity quadratic interaction revealed that children with decelerations in RSA reactivity exhibited increases in behavioral dysregulation, regardless of their exposure to early adversity. However, greater exposure to early adversity was related to greater increases in behavioral dysregulation, but only if children exhibited accelerations in RSA reactivity from ages 3 to 6 years. The results contribute to our understanding of how interactions across multiple levels of analysis contribute to the development of ND.

AB - Neurobehavioral disinhibition (ND) is a complex condition reflecting a wide range of problems involving difficulties with emotion regulation and behavior control. Respiratory sinus arrhythmia (RSA) is a physiological correlate of emotion regulation that has been studied in a variety of at-risk populations; however, there are no studies of RSA in children with ND. Data were drawn from a prospective longitudinal study of prenatal substance exposure that included 1,073 participants. Baseline RSA and RSA reactivity to an attention-demanding task were assessed at 3, 4, 5, and 6 years. ND was assessed at ages 8/9, 11, and 13/14 years via behavioral dysregulation and executive dysfunction composite measures. Greater exposure to early adversity was related to less RSA reactivity at 3 years, increases in RSA reactivity from ages 3 to 6 years, and increased behavioral dysregulation from ages 8/9 to 13/14. RSA reactivity was examined as a moderator of the association between early adversity and changes in ND. A significant Early Adversity × RSA Reactivity quadratic interaction revealed that children with decelerations in RSA reactivity exhibited increases in behavioral dysregulation, regardless of their exposure to early adversity. However, greater exposure to early adversity was related to greater increases in behavioral dysregulation, but only if children exhibited accelerations in RSA reactivity from ages 3 to 6 years. The results contribute to our understanding of how interactions across multiple levels of analysis contribute to the development of ND.

UR - http://www.scopus.com/inward/record.url?scp=84991461456&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84991461456&partnerID=8YFLogxK

U2 - 10.1017/S095457941400056X

DO - 10.1017/S095457941400056X

M3 - Article

C2 - 24909973

AN - SCOPUS:84991461456

VL - 26

SP - 901

EP - 916

JO - Development and Psychopathology

JF - Development and Psychopathology

SN - 0954-5794

IS - 4

ER -