Abstract
Objective: The recently developed cognitive change checklist (3CL) is comprised of four scales titled memory, executive, language, and remote recall. A previous study demonstrated that the checklist met criteria for reliability and validity in characterizing cases of mild cognitive impairment (MCI) and early dementia in a memory disorder clinic sample. In this study we examined further the reliability, validity, and efficacy of the 3CL in distinguishing among groups of normal individuals, those with cognitive complaints, amnestic and non-amnestic MCI cases, and early-stage demented individuals. Design: Scale validation study. Setting: Alzheimer's Disease Research Center Participants: One hundred and twenty-five individuals who completed extensive evaluations as part of a longitudinal study of cognitive change. Results: Scale reliabilities were found to be well within guidelines to support their use in the clinical assessment of change in global and specific cognitive domains. The factor structure of the 3CL was found to be highly similar to that originally reported. Validation support was obtained from correlational analyses that showed significant scale relationships with neurocognitive measures and with MRI ratings of medial temporal atrophy. Informant 3CL scales were found to discriminate individuals with cognitive complaints but without clinical findings from those individuals with amnestic MCI or early dementia. Conclusion: Results extend the foundation of support for the use of the 3CL as a measure to facilitate identification of cases of MCI and early AD. Further examination of the diagnostic utility of the scale, and of its value in combination with cognitive screening measures, will also be required.
| Original language | English |
|---|---|
| Pages (from-to) | 266-274 |
| Number of pages | 9 |
| Journal | International Journal of Geriatric Psychiatry |
| Volume | 25 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1 2010 |
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Keywords
- Aging
- Cognition
- Cognitive decline
- Dementia
- Everyday cognition
- Everyday function
- Mild cognitive impairment
- Rating scales
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Psychiatry and Mental health
Cite this
The cognitive change checklist (3CL) : Cross-validation of a measure of change in everyday cognition. / Schinka, John A.; Raj, Ashok; Loewenstein, David; Small, Brent J.; Duara, Ranjan; Potter, Huntington.
In: International Journal of Geriatric Psychiatry, Vol. 25, No. 3, 01.03.2010, p. 266-274.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The cognitive change checklist (3CL)
T2 - Cross-validation of a measure of change in everyday cognition
AU - Schinka, John A.
AU - Raj, Ashok
AU - Loewenstein, David
AU - Small, Brent J.
AU - Duara, Ranjan
AU - Potter, Huntington
PY - 2010/3/1
Y1 - 2010/3/1
N2 - Objective: The recently developed cognitive change checklist (3CL) is comprised of four scales titled memory, executive, language, and remote recall. A previous study demonstrated that the checklist met criteria for reliability and validity in characterizing cases of mild cognitive impairment (MCI) and early dementia in a memory disorder clinic sample. In this study we examined further the reliability, validity, and efficacy of the 3CL in distinguishing among groups of normal individuals, those with cognitive complaints, amnestic and non-amnestic MCI cases, and early-stage demented individuals. Design: Scale validation study. Setting: Alzheimer's Disease Research Center Participants: One hundred and twenty-five individuals who completed extensive evaluations as part of a longitudinal study of cognitive change. Results: Scale reliabilities were found to be well within guidelines to support their use in the clinical assessment of change in global and specific cognitive domains. The factor structure of the 3CL was found to be highly similar to that originally reported. Validation support was obtained from correlational analyses that showed significant scale relationships with neurocognitive measures and with MRI ratings of medial temporal atrophy. Informant 3CL scales were found to discriminate individuals with cognitive complaints but without clinical findings from those individuals with amnestic MCI or early dementia. Conclusion: Results extend the foundation of support for the use of the 3CL as a measure to facilitate identification of cases of MCI and early AD. Further examination of the diagnostic utility of the scale, and of its value in combination with cognitive screening measures, will also be required.
AB - Objective: The recently developed cognitive change checklist (3CL) is comprised of four scales titled memory, executive, language, and remote recall. A previous study demonstrated that the checklist met criteria for reliability and validity in characterizing cases of mild cognitive impairment (MCI) and early dementia in a memory disorder clinic sample. In this study we examined further the reliability, validity, and efficacy of the 3CL in distinguishing among groups of normal individuals, those with cognitive complaints, amnestic and non-amnestic MCI cases, and early-stage demented individuals. Design: Scale validation study. Setting: Alzheimer's Disease Research Center Participants: One hundred and twenty-five individuals who completed extensive evaluations as part of a longitudinal study of cognitive change. Results: Scale reliabilities were found to be well within guidelines to support their use in the clinical assessment of change in global and specific cognitive domains. The factor structure of the 3CL was found to be highly similar to that originally reported. Validation support was obtained from correlational analyses that showed significant scale relationships with neurocognitive measures and with MRI ratings of medial temporal atrophy. Informant 3CL scales were found to discriminate individuals with cognitive complaints but without clinical findings from those individuals with amnestic MCI or early dementia. Conclusion: Results extend the foundation of support for the use of the 3CL as a measure to facilitate identification of cases of MCI and early AD. Further examination of the diagnostic utility of the scale, and of its value in combination with cognitive screening measures, will also be required.
KW - Aging
KW - Cognition
KW - Cognitive decline
KW - Dementia
KW - Everyday cognition
KW - Everyday function
KW - Mild cognitive impairment
KW - Rating scales
UR - http://www.scopus.com/inward/record.url?scp=76649090305&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=76649090305&partnerID=8YFLogxK
U2 - 10.1002/gps.2332
DO - 10.1002/gps.2332
M3 - Article
C2 - 19575419
AN - SCOPUS:76649090305
VL - 25
SP - 266
EP - 274
JO - International Journal of Geriatric Psychiatry
JF - International Journal of Geriatric Psychiatry
SN - 0885-6230
IS - 3
ER -