The Chediak-Higashi-Steinbrinck Syndrome: Presentation of Three Cases with Features Resembling Spinocerebellar Degeneration

William Sheramata, H. Stephen Kott, Donat P. Cyr

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

Three patients with Chediak-Higashi-Steinbrinck syndrome and clinical pictures resembling a spinocerebellar degeneration are older than any patients previously reported. Including this report, six of 38 cases in the English literature have presented evidence of similar neurologic pictures. Pathologic evidence of reported cases and animal work support the conclusion that a form of spinocerebellar degeneration is, to some extent, a regular part of the varied clinical and pathologic manifestations comprising this syndrome.

Original languageEnglish (US)
Pages (from-to)289-294
Number of pages6
JournalArchives of neurology
Volume25
Issue number4
DOIs
StatePublished - Oct 1971

Keywords

  • Chediak-Higashi-Steinbrinck syndrome
  • cellular infiltration
  • hematologic features
  • spinocerebellar degeneration

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

Fingerprint Dive into the research topics of 'The Chediak-Higashi-Steinbrinck Syndrome: Presentation of Three Cases with Features Resembling Spinocerebellar Degeneration'. Together they form a unique fingerprint.

  • Cite this