The challenges of implementing low-dose computed tomography for lung cancer screening in low- and middle-income countries

Eduardo Edelman Saul, Raquel B. Guerra, Michelle Edelman Saul, Laercio Lopes da Silva, Gabriel F.P. Aleixo, Raquel M.K. Matuda, Gilberto Lopes

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Lung cancer accounts for an alarming human and economic burden in low- and middle-income countries (LMICs). Recent landmark trials from high-income countries (HICs) by demonstrating that low-dose computed tomography (LDCT) screening effectively reduces lung cancer mortality have engendered enthusiasm for this approach. Here we examine the effectiveness and affordability of LDCT screening from the viewpoint of LMICs. We consider resource-restricted perspectives and discuss implementation challenges and strategies to enhance the feasibility and cost-effectiveness of LDCT screening in LMICs.

Original languageEnglish (US)
Pages (from-to)1140-1152
Number of pages13
JournalNature Cancer
Volume1
Issue number12
DOIs
StatePublished - Dec 2020

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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