The C5b-9 complex: subunit composition of the classical and alternative pathway generated complex

E. R. Podack, W. P. Kolb, H. J. Muller Eberhard

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

The membrane attack complex of complement (C5b 9) is identical in composition regardless of which pathway of activation was instrumental in its formation. Band V protein was consistently a subunit of the soluble complex. Since band V protein is not required for complement dependent cytolysis, it probably represents a membrane site equivalent in serum of the nascent C5b 9 complex.

Original languageEnglish (US)
Pages (from-to)1431-1434
Number of pages4
JournalJournal of Immunology
Volume116
Issue number5
StatePublished - Dec 1 1976

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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