Abstract
The cytoplasm is usually a DNA-free zone, but during fertilization, sperm DNA enters oocyte cytoplasm and could potentially trigger a response. Abe et al. (2017) identify NLRP14 as a germ-cell-specific negative regulator of DNA sensing that may be of particular importance during fertilization.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 521-522 |
| Number of pages | 2 |
| Journal | Immunity |
| Volume | 46 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 18 2017 |
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ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Infectious Diseases
Cite this
The Birds, the Bees, and Innate Immunity. / Barber, Glen N.
In: Immunity, Vol. 46, No. 4, 18.04.2017, p. 521-522.Research output: Contribution to journal › Short survey
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TY - JOUR
T1 - The Birds, the Bees, and Innate Immunity
AU - Barber, Glen N
PY - 2017/4/18
Y1 - 2017/4/18
N2 - The cytoplasm is usually a DNA-free zone, but during fertilization, sperm DNA enters oocyte cytoplasm and could potentially trigger a response. Abe et al. (2017) identify NLRP14 as a germ-cell-specific negative regulator of DNA sensing that may be of particular importance during fertilization.
AB - The cytoplasm is usually a DNA-free zone, but during fertilization, sperm DNA enters oocyte cytoplasm and could potentially trigger a response. Abe et al. (2017) identify NLRP14 as a germ-cell-specific negative regulator of DNA sensing that may be of particular importance during fertilization.
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UR - http://www.scopus.com/inward/citedby.url?scp=85018928139&partnerID=8YFLogxK
U2 - 10.1016/j.immuni.2017.04.002
DO - 10.1016/j.immuni.2017.04.002
M3 - Short survey
C2 - 28423330
AN - SCOPUS:85018928139
VL - 46
SP - 521
EP - 522
JO - Immunity
JF - Immunity
SN - 1074-7613
IS - 4
ER -