The biogenesis of glycogen: Nature of the carbohydrate in the protein primer

J. Lomako, W. M. Lomako, William J. Whelan

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Glycogen synthesis in rabbit muscle takes place on an autocatalytic protein that glucosylates itself to form a maltosaccharide that in turn primes the actions of glycogen synthase and branching enzyme to form glycogen. Here we show that in the form in which the protein is isolated from muscle it already contains one molecular proportion of a maltosaccharide ranging in length from 2 to 8 glucose residues. Self-glucosylation consists in the lengthening of all the chains to become malto-octaose.

Original languageEnglish
Pages (from-to)251-260
Number of pages10
JournalBiochemistry International
Volume21
Issue number2
StatePublished - Jul 20 1990

Fingerprint

Glycogen
Muscle
1,4-alpha-Glucan Branching Enzyme
Carbohydrates
Muscles
Glycogen Synthase
Proteins
Rabbits
Glucose

ASJC Scopus subject areas

  • Biochemistry

Cite this

The biogenesis of glycogen : Nature of the carbohydrate in the protein primer. / Lomako, J.; Lomako, W. M.; Whelan, William J.

In: Biochemistry International, Vol. 21, No. 2, 20.07.1990, p. 251-260.

Research output: Contribution to journalArticle

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