The associations between basal salivary cortisol and illness symptomatology in chronic fatigue syndrome

Susan Torres-Harding, Matthew Sorenson, Leonard Jason, Nadia Reynolds, Molly Brown, Kevin Maher, Mary Ann Fletcher

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Hypocortisolism has been reported in chronic fatigue syndrome (CFS), with the significance of this finding to disease etiology unclear. This study examined cortisol levels and their relationships with symptoms in a group of 108 individuals with CFS. CFS symptoms examined included fatigue, pain, sleep difficulties, neurocognitive functioning, and psychiatric status. Alterations in cortisol levels were examined by calculation of mean daily cortisol, and temporal variation in cortisol function was examined by means of a regression slope. Additionally, deviation from expected cortisol diurnal pattern was determined via clinical judgment. Results indicated that fatigue and pain were associated with salivary cortisol levels. In particular, variance from the expected pattern of cortisol was associated with increased levels of fatigue. The implications of these findings are discussed.

Original languageEnglish
Pages (from-to)157-180
Number of pages24
JournalJournal of Applied Biobehavioral Research
Volume13
Issue number3
DOIs
StatePublished - Jul 1 2008
Externally publishedYes

Fingerprint

Chronic Fatigue Syndrome
fatigue
Hydrocortisone
illness
Fatigue
pain
Pain
etiology
sleep
Psychiatry
Sleep
Disease
regression
Group

ASJC Scopus subject areas

  • Social Sciences (miscellaneous)
  • Clinical Psychology
  • Experimental and Cognitive Psychology
  • Cultural Studies

Cite this

The associations between basal salivary cortisol and illness symptomatology in chronic fatigue syndrome. / Torres-Harding, Susan; Sorenson, Matthew; Jason, Leonard; Reynolds, Nadia; Brown, Molly; Maher, Kevin; Fletcher, Mary Ann.

In: Journal of Applied Biobehavioral Research, Vol. 13, No. 3, 01.07.2008, p. 157-180.

Research output: Contribution to journalArticle

Torres-Harding, S, Sorenson, M, Jason, L, Reynolds, N, Brown, M, Maher, K & Fletcher, MA 2008, 'The associations between basal salivary cortisol and illness symptomatology in chronic fatigue syndrome', Journal of Applied Biobehavioral Research, vol. 13, no. 3, pp. 157-180. https://doi.org/10.1111/j.1751-9861.2008.00033.x
Torres-Harding, Susan ; Sorenson, Matthew ; Jason, Leonard ; Reynolds, Nadia ; Brown, Molly ; Maher, Kevin ; Fletcher, Mary Ann. / The associations between basal salivary cortisol and illness symptomatology in chronic fatigue syndrome. In: Journal of Applied Biobehavioral Research. 2008 ; Vol. 13, No. 3. pp. 157-180.
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