The association of affective disorder with Huntington's Disease in a case series and in families

S. E. Folstein, M. H. Abbott, G. A. Chase, B. A. Jensen

Research output: Contribution to journalArticle

162 Citations (Scopus)

Abstract

Major affective disorder clinically similar to the disorder found in conditions other than Huntington's Disease (HD) was found in 41% of patients with HD in a consecutive case series ascertained through multiple sources in a defined geographical area. The association appears to be confined to certain families, and affective disorder may appear as long as 20 years before the onset of chorea and dementia. The association may represent genetic heterogeneity in HD.

Original languageEnglish
Pages (from-to)537-542
Number of pages6
JournalPsychological Medicine
Volume13
Issue number3
StatePublished - Dec 1 1983

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Huntington Disease
Mood Disorders
Chorea
Genetic Heterogeneity
Dementia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Psychology(all)
  • Clinical Psychology

Cite this

Folstein, S. E., Abbott, M. H., Chase, G. A., & Jensen, B. A. (1983). The association of affective disorder with Huntington's Disease in a case series and in families. Psychological Medicine, 13(3), 537-542.

The association of affective disorder with Huntington's Disease in a case series and in families. / Folstein, S. E.; Abbott, M. H.; Chase, G. A.; Jensen, B. A.

In: Psychological Medicine, Vol. 13, No. 3, 01.12.1983, p. 537-542.

Research output: Contribution to journalArticle

Folstein, SE, Abbott, MH, Chase, GA & Jensen, BA 1983, 'The association of affective disorder with Huntington's Disease in a case series and in families', Psychological Medicine, vol. 13, no. 3, pp. 537-542.
Folstein, S. E. ; Abbott, M. H. ; Chase, G. A. ; Jensen, B. A. / The association of affective disorder with Huntington's Disease in a case series and in families. In: Psychological Medicine. 1983 ; Vol. 13, No. 3. pp. 537-542.
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