The association between plant-based content in diet and testosterone levels in US adults

Manish Kuchakulla, Sirpi Nackeeran, Ruben Blachman-Braun, Ranjith Ramasamy

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Purpose: To evaluate the association between the plant-based content of diet and serum testosterone levels in men from the national health and nutrition examination survey (NHANES) database. Materials and methods: Data on demographics, diet, and testosterone levels was acquired from the NHANES database. Using the food frequency questionnaire, an overall plant-based diet index (PDI) and a healthful plant-based diet index (hPDI) was developed. A higher score on PDI and hPDI indicates higher consumption of plant foods. Results: A total of 191 participants were included, average age was 45 (30–60) years and average total testosterone level was 546.7 ± 254.7 ng/dL. The mean PDI and hPDI were 50.4 ± 6 and 50.8 ± 7.2, respectively. On multiple linear regression analysis, BMI and age significantly contribute to testosterone levels (p < 0.05); however, neither of the diet indexes significantly predicted serum testosterone levels (PDI: p = 0.446; and hPDI: p = 0.056). Conclusions: In a well characterized national database, the plant-based diet index is unable to predict testosterone levels. Plant-based food content in diet is not associated with serum testosterone levels.

Original languageEnglish (US)
Pages (from-to)1307-1311
Number of pages5
JournalWorld journal of urology
Issue number4
StatePublished - Apr 2021


  • Diet
  • Index
  • Plant-based diet
  • Testosterone
  • Vegan
  • Vegetarian

ASJC Scopus subject areas

  • Urology


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