The association between heart rate and glycemia in adult diabetic subjects

Maria T. Gadia, Jay S. Skyler, Jay M. Sosenko

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


We have studied the association between heart rate and glycemia in 221 diabetic and 109 non-diabetic adult subjects. Supine and standing heart rates were both statistically significantly higher (P < 0.001) in the diabetic patients than in the control subjects. Among the diabetics, both the supine and standing heart rates were positively associated with hemoglobin A1c (r = 0.26, P < 0.001 and r = 0.27, P < 0.001 respectively). Patients with hemoglobin A1c values greater than 10.00% had a mean heart rate of 84.2 ± 2.4, while those with hemoglobin A1c values less than 6.00% had a mean of 74.0 ± 1.5 (P < 0.001). The associations between heart rate and hemoglobin A1c persisted (P < 0.001) with allowances for potential confounding variables in multiple regression analyses. The 15:30 difference, an indicator of parasympathetic function, was not associated with either heart rate or glycemia. These data suggest that the heart rate elevation in adult diabetic patients is the result of metabolic abnormalities.

Original languageEnglish (US)
Pages (from-to)25-29
Number of pages5
JournalDiabetes research and clinical practice
Issue number1
StatePublished - May 19 1988


  • (Diabetes mellitus)
  • Glycosylated hemoglobin
  • Heart rate

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine


Dive into the research topics of 'The association between heart rate and glycemia in adult diabetic subjects'. Together they form a unique fingerprint.

Cite this