The aspartate-257 of presenilin 1 is indispensable for mouse development and production of β-amyloid peptides through β-catenin-independent mechanisms

Xuefeng Xia, Pei Wang, Xiaoyan Sun, Salvador Soriano, Wan Kyng Shum, Haruyasu Yamaguchi, Myrna E. Trumbauer, Akihiko Takashima, Edward H. Koo, Hui Zheng

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Medicine & Life Sciences