The antimicrobial susceptibility patterns of the barteroides fragilis group in the united states, 1987

N. A. Cornick, G. J. Cuchural, D. R. Snydman, N. V. Jacobus, P. Iannini, G. Hill, T. Cleary, J. P. O'keefe, C. Pierson, S. M. Finegold

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Abstract

A nationwide survey to monitor the susceptibility of the Bacteroides fragilis group, which began in 1981, was continued during 1987. In addition to the eleven drugs evaluated in 1986, sulbactam, a potent β-lactamase inhibitor, was tested alone and in combination with amipicillin and cefoperazone. Imipenem, ampicillin/sulbactam cefoperazone/sulbactam, and ticarcillin/clavulanic acid were the most active newer drugs tested, with less than 1% resistance rates. Chloramphenicol, metronidazole and clindamycin also had excellent activity with resistance rates of 0%, 0%, and 3% respectively. Resistance rates to cefoxitin remained stable at 8%. Ceftizoxime and cefotetan had resistance rates of 26% and 29%, respectively. Rates of resistance varied among different institutions and between the various species.

Original languageEnglish (US)
Pages (from-to)1011-1019
Number of pages9
JournalJournal of Antimicrobial Chemotherapy
Volume25
Issue number6
DOIs
StatePublished - Jun 1 1990

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ASJC Scopus subject areas

  • Pharmacology
  • Microbiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)

Cite this

Cornick, N. A., Cuchural, G. J., Snydman, D. R., Jacobus, N. V., Iannini, P., Hill, G., Cleary, T., O'keefe, J. P., Pierson, C., & Finegold, S. M. (1990). The antimicrobial susceptibility patterns of the barteroides fragilis group in the united states, 1987. Journal of Antimicrobial Chemotherapy, 25(6), 1011-1019. https://doi.org/10.1093/jac/25.6.1011