The anonymous RFLP locus D1S2 is close to PGM1 on chromosome 1

K. K. Kidd, J. R. Kidd, C. M. Castiglione, R. S. Sparkes, J. A. Egeland, E. Bakker

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

D1S2 was one of the first restriction fragment length polymorphisms (RFLPs) assigned to chromosome 1, but its regional location was unknown. In this paper we present data that place this RFLP into both the genetic map and the physical-cytogenetic map. Linkage data maps D1S2 7 cM from PGM1, which is localized to the middle of the short arm at 1p22.1. Southern blot analysis of DNA samples from somatic cell hybrids containing parts of chromosome 1 maps D1S2 proximal to 1p32 and distal to PGM1.

Original languageEnglish (US)
Pages (from-to)22-26
Number of pages5
JournalHuman Heredity
Volume38
Issue number1
DOIs
StatePublished - Jan 1 1988

Keywords

  • Chromosome 1
  • D1S2
  • Linkage
  • Mapping
  • PGM1
  • RFLP
  • Somatic cell hybrid

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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    Kidd, K. K., Kidd, J. R., Castiglione, C. M., Sparkes, R. S., Egeland, J. A., & Bakker, E. (1988). The anonymous RFLP locus D1S2 is close to PGM1 on chromosome 1. Human Heredity, 38(1), 22-26. https://doi.org/10.1159/000153749