The Acute Retinal Necrosis Syndrome: Part 1: Clinical Manifestations

Jerome P. Fisher, Mary Lou Lewis, Mark Blumenkranz, William W. Culbertson, Harry W. Flynn, John G. Clarkson, J. Donald M. Gass, Edward W.D. Norton

Research output: Contribution to journalArticlepeer-review

175 Scopus citations


The acute retinal necrosis syndrome is characterized by necrotizing retinitis, vitritis, and retinal vasculitis occurring in otherwise healthy patients. Experience with 11 cases and the review of 30 additional cases in the literature are presented. In this series, 50% of the affected eyes developed retinal detachments, and 64% had a final visual acuity of less than 20/200. The natural history, diagnosis, postulated etiology, and suggestions for management will be discussed.

Original languageEnglish (US)
Pages (from-to)1309-1316
Number of pages8
Issue number12
StatePublished - 1982


  • adenine arabinoside
  • herpes virus
  • necrotizing retinitis
  • retinitis
  • uveitus
  • vasculitis
  • viral retinitis
  • vitritis

ASJC Scopus subject areas

  • Ophthalmology


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