Abstract
The records of 292 patients with acute pulmonary edema were reviewed to determine the frequency, severity and type of acid-base abnormalities. Arterial blood gas analyses were available in 109 patients, including eight patients with submersion complicated by pulmonary edema. Of the 101 cardiac cases, a severe combined metabolic and respiratory acidosis was present in fifty-five, with mean pH 7.11, carbon dioxide pressure (pCO2) 70 mm Hg and base excess -10 mEq per L. There were fourteen patients with metabolic acidosis, twelve with respiratory acidosis and eight with respiratory alkalosis. Four of the eight patients in the submersion group exhibited a combined acidosis. Treatment included mechanical ventilation, intubation when indicated, and intravenously administered sodium bicarbonate, in addition to conventional therapy for pulmonary edema. Combined respiratory and metabolic acidosis probably occurs in approximately 25 per cent of patients with acute pulmonary edema, and metabolic or respiratory acidosis in another 10 per cent. Serial arterial blood gas analyses are a prerequisite for physiologically appropriate management of these patients.
| Original language | English |
|---|---|
| Pages (from-to) | 320-324 |
| Number of pages | 5 |
| Journal | The American Journal of Medicine |
| Volume | 48 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jan 1 1970 |
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The acidosis of pulmonary edema. / Avery, Wilbur G.; Samet, Philip; Sackner, Marvin A.
In: The American Journal of Medicine, Vol. 48, No. 3, 01.01.1970, p. 320-324.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The acidosis of pulmonary edema
AU - Avery, Wilbur G.
AU - Samet, Philip
AU - Sackner, Marvin A.
PY - 1970/1/1
Y1 - 1970/1/1
N2 - The records of 292 patients with acute pulmonary edema were reviewed to determine the frequency, severity and type of acid-base abnormalities. Arterial blood gas analyses were available in 109 patients, including eight patients with submersion complicated by pulmonary edema. Of the 101 cardiac cases, a severe combined metabolic and respiratory acidosis was present in fifty-five, with mean pH 7.11, carbon dioxide pressure (pCO2) 70 mm Hg and base excess -10 mEq per L. There were fourteen patients with metabolic acidosis, twelve with respiratory acidosis and eight with respiratory alkalosis. Four of the eight patients in the submersion group exhibited a combined acidosis. Treatment included mechanical ventilation, intubation when indicated, and intravenously administered sodium bicarbonate, in addition to conventional therapy for pulmonary edema. Combined respiratory and metabolic acidosis probably occurs in approximately 25 per cent of patients with acute pulmonary edema, and metabolic or respiratory acidosis in another 10 per cent. Serial arterial blood gas analyses are a prerequisite for physiologically appropriate management of these patients.
AB - The records of 292 patients with acute pulmonary edema were reviewed to determine the frequency, severity and type of acid-base abnormalities. Arterial blood gas analyses were available in 109 patients, including eight patients with submersion complicated by pulmonary edema. Of the 101 cardiac cases, a severe combined metabolic and respiratory acidosis was present in fifty-five, with mean pH 7.11, carbon dioxide pressure (pCO2) 70 mm Hg and base excess -10 mEq per L. There were fourteen patients with metabolic acidosis, twelve with respiratory acidosis and eight with respiratory alkalosis. Four of the eight patients in the submersion group exhibited a combined acidosis. Treatment included mechanical ventilation, intubation when indicated, and intravenously administered sodium bicarbonate, in addition to conventional therapy for pulmonary edema. Combined respiratory and metabolic acidosis probably occurs in approximately 25 per cent of patients with acute pulmonary edema, and metabolic or respiratory acidosis in another 10 per cent. Serial arterial blood gas analyses are a prerequisite for physiologically appropriate management of these patients.
UR - http://www.scopus.com/inward/record.url?scp=0014748386&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0014748386&partnerID=8YFLogxK
U2 - 10.1016/0002-9343(70)90062-8
DO - 10.1016/0002-9343(70)90062-8
M3 - Article
C2 - 5265250
AN - SCOPUS:0014748386
VL - 48
SP - 320
EP - 324
JO - American Journal of Medicine
JF - American Journal of Medicine
SN - 0002-9343
IS - 3
ER -