The acidosis of pulmonary edema

Wilbur G. Avery, Philip Samet, Marvin A. Sackner

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The records of 292 patients with acute pulmonary edema were reviewed to determine the frequency, severity and type of acid-base abnormalities. Arterial blood gas analyses were available in 109 patients, including eight patients with submersion complicated by pulmonary edema. Of the 101 cardiac cases, a severe combined metabolic and respiratory acidosis was present in fifty-five, with mean pH 7.11, carbon dioxide pressure (pCO2) 70 mm Hg and base excess -10 mEq per L. There were fourteen patients with metabolic acidosis, twelve with respiratory acidosis and eight with respiratory alkalosis. Four of the eight patients in the submersion group exhibited a combined acidosis. Treatment included mechanical ventilation, intubation when indicated, and intravenously administered sodium bicarbonate, in addition to conventional therapy for pulmonary edema. Combined respiratory and metabolic acidosis probably occurs in approximately 25 per cent of patients with acute pulmonary edema, and metabolic or respiratory acidosis in another 10 per cent. Serial arterial blood gas analyses are a prerequisite for physiologically appropriate management of these patients.

Original languageEnglish
Pages (from-to)320-324
Number of pages5
JournalThe American Journal of Medicine
Volume48
Issue number3
DOIs
StatePublished - Jan 1 1970

Fingerprint

Pulmonary Edema
Acidosis
Respiratory Acidosis
Blood Gas Analysis
Immersion
Respiratory Alkalosis
Sodium Bicarbonate
Artificial Respiration
Intubation
Carbon Dioxide
Pressure
Acids
Therapeutics

ASJC Scopus subject areas

  • Nursing(all)

Cite this

The acidosis of pulmonary edema. / Avery, Wilbur G.; Samet, Philip; Sackner, Marvin A.

In: The American Journal of Medicine, Vol. 48, No. 3, 01.01.1970, p. 320-324.

Research output: Contribution to journalArticle

Avery, WG, Samet, P & Sackner, MA 1970, 'The acidosis of pulmonary edema', The American Journal of Medicine, vol. 48, no. 3, pp. 320-324. https://doi.org/10.1016/0002-9343(70)90062-8
Avery, Wilbur G. ; Samet, Philip ; Sackner, Marvin A. / The acidosis of pulmonary edema. In: The American Journal of Medicine. 1970 ; Vol. 48, No. 3. pp. 320-324.
@article{1991cdb7793440e1af81dbaafc2d5467,
title = "The acidosis of pulmonary edema",
abstract = "The records of 292 patients with acute pulmonary edema were reviewed to determine the frequency, severity and type of acid-base abnormalities. Arterial blood gas analyses were available in 109 patients, including eight patients with submersion complicated by pulmonary edema. Of the 101 cardiac cases, a severe combined metabolic and respiratory acidosis was present in fifty-five, with mean pH 7.11, carbon dioxide pressure (pCO2) 70 mm Hg and base excess -10 mEq per L. There were fourteen patients with metabolic acidosis, twelve with respiratory acidosis and eight with respiratory alkalosis. Four of the eight patients in the submersion group exhibited a combined acidosis. Treatment included mechanical ventilation, intubation when indicated, and intravenously administered sodium bicarbonate, in addition to conventional therapy for pulmonary edema. Combined respiratory and metabolic acidosis probably occurs in approximately 25 per cent of patients with acute pulmonary edema, and metabolic or respiratory acidosis in another 10 per cent. Serial arterial blood gas analyses are a prerequisite for physiologically appropriate management of these patients.",
author = "Avery, {Wilbur G.} and Philip Samet and Sackner, {Marvin A.}",
year = "1970",
month = "1",
day = "1",
doi = "10.1016/0002-9343(70)90062-8",
language = "English",
volume = "48",
pages = "320--324",
journal = "American Journal of Medicine",
issn = "0002-9343",
publisher = "Elsevier Inc.",
number = "3",

}

TY - JOUR

T1 - The acidosis of pulmonary edema

AU - Avery, Wilbur G.

AU - Samet, Philip

AU - Sackner, Marvin A.

PY - 1970/1/1

Y1 - 1970/1/1

N2 - The records of 292 patients with acute pulmonary edema were reviewed to determine the frequency, severity and type of acid-base abnormalities. Arterial blood gas analyses were available in 109 patients, including eight patients with submersion complicated by pulmonary edema. Of the 101 cardiac cases, a severe combined metabolic and respiratory acidosis was present in fifty-five, with mean pH 7.11, carbon dioxide pressure (pCO2) 70 mm Hg and base excess -10 mEq per L. There were fourteen patients with metabolic acidosis, twelve with respiratory acidosis and eight with respiratory alkalosis. Four of the eight patients in the submersion group exhibited a combined acidosis. Treatment included mechanical ventilation, intubation when indicated, and intravenously administered sodium bicarbonate, in addition to conventional therapy for pulmonary edema. Combined respiratory and metabolic acidosis probably occurs in approximately 25 per cent of patients with acute pulmonary edema, and metabolic or respiratory acidosis in another 10 per cent. Serial arterial blood gas analyses are a prerequisite for physiologically appropriate management of these patients.

AB - The records of 292 patients with acute pulmonary edema were reviewed to determine the frequency, severity and type of acid-base abnormalities. Arterial blood gas analyses were available in 109 patients, including eight patients with submersion complicated by pulmonary edema. Of the 101 cardiac cases, a severe combined metabolic and respiratory acidosis was present in fifty-five, with mean pH 7.11, carbon dioxide pressure (pCO2) 70 mm Hg and base excess -10 mEq per L. There were fourteen patients with metabolic acidosis, twelve with respiratory acidosis and eight with respiratory alkalosis. Four of the eight patients in the submersion group exhibited a combined acidosis. Treatment included mechanical ventilation, intubation when indicated, and intravenously administered sodium bicarbonate, in addition to conventional therapy for pulmonary edema. Combined respiratory and metabolic acidosis probably occurs in approximately 25 per cent of patients with acute pulmonary edema, and metabolic or respiratory acidosis in another 10 per cent. Serial arterial blood gas analyses are a prerequisite for physiologically appropriate management of these patients.

UR - http://www.scopus.com/inward/record.url?scp=0014748386&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0014748386&partnerID=8YFLogxK

U2 - 10.1016/0002-9343(70)90062-8

DO - 10.1016/0002-9343(70)90062-8

M3 - Article

VL - 48

SP - 320

EP - 324

JO - American Journal of Medicine

JF - American Journal of Medicine

SN - 0002-9343

IS - 3

ER -