Test of a web-based program to improve adherence to HIV medications

Rebekah K. Hersch, Royer F. Cook, Douglas W. Billings, Seth Kaplan, David Murray, Steven Safren, Justin Goforth, Joy Spencer

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


We evaluated the effectiveness of a web-based version of the Life-Steps intervention combined with modules for stress reduction and mood management, designed to improve medication adherence among HIV infected individuals. 168 HIV+ adults were randomized into either the Life-Steps program or a waitlist control condition. All participants completed a baseline assessment and provided a 2-week electronic pill (MEMS) cap baseline reading. Follow up data collection was conducted at 3, 6 and 9 months. Patients in the web-based Life-Steps condition had significantly higher antiretroviral medication adherence rates than patients in the control group over the nine-month period as measured by the MEMS cap. In addition, analysis of viral load data indicated that the program also resulted in a significant decrease in viral load. These findings indicate that a web-based Life-Steps program can be a useful and implementable tool for helping patients living with HIV maintain medication adherence.

Original languageEnglish (US)
Pages (from-to)2963-2976
Number of pages14
JournalAIDS and Behavior
Issue number9
StatePublished - Nov 2013
Externally publishedYes


  • ART
  • Antiretroviral therapy
  • Medication adherence
  • Web-based program

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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