Terminal Carboxylate Effects on the Thermodynamics and Kinetics of Cucurbit[7]uril Binding to Guests Containing a Central Bis(Pyridinium)-Xylylene Site

Iago Neira, Marcos D. García, Carlos Peinador, Angel Kaifer

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

A series of bis(pyridinium)-xylylene derivatives bearing carboxylate terminal groups were investigated as guests for the cucurbit[7]uril host in aqueous solution. While the presence of the terminal carboxylates has a modest effect on the thermodynamic stability of the complexes, the kinetics of complex association/dissociation is strongly affected. The relative position ( meta, para) of the carboxylate group in relation to the pyridinium nitrogen also exerts a considerable effect on the binding kinetics.

Original languageEnglish (US)
Pages (from-to)2325-2329
Number of pages5
JournalThe Journal of organic chemistry
Volume84
Issue number4
DOIs
StatePublished - Feb 15 2019

    Fingerprint

ASJC Scopus subject areas

  • Organic Chemistry

Cite this