Temporary pituitary insensitivity to stimulation by synthetic LRF during the postpartum period

W. J. LeMaire; A. G. Shapiro; F. Riggall; N. S.T. Yang

doi:10.1210/jcem-38-5-916

Temporary pituitary insensitivity to stimulation by synthetic LRF during the postpartum period

W. J. LeMaire, A. G. Shapiro, F. Riggall, N. S.T. Yang

Obstetrics & Gynecology

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Following a subcutaneous injection of 100 μg of synthetic luteinizing hormone releasing factor (LRF), no increase was seen in the plasma luteinizing hormone (LH) in 3 subjects (1 nursing, 2 not nursing) studied in the first 3 wk after delivery. When studied again 6 wk or later after delivery, a normal increase was observed in plasma LH following LRF administration. These studies suggest that the pituitary gland might be temporarily resistant to stimulation by LRF in the early postpartum period.

Original language	English (US)
Pages (from-to)	916-918
Number of pages	3
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	38
Issue number	5
DOIs	https://doi.org/10.1210/jcem-38-5-916
State	Published - Jan 1 1974

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Biochemistry
Endocrinology
Clinical Biochemistry
Biochemistry, medical

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1210/jcem-38-5-916

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N2 - Following a subcutaneous injection of 100 μg of synthetic luteinizing hormone releasing factor (LRF), no increase was seen in the plasma luteinizing hormone (LH) in 3 subjects (1 nursing, 2 not nursing) studied in the first 3 wk after delivery. When studied again 6 wk or later after delivery, a normal increase was observed in plasma LH following LRF administration. These studies suggest that the pituitary gland might be temporarily resistant to stimulation by LRF in the early postpartum period.

AB - Following a subcutaneous injection of 100 μg of synthetic luteinizing hormone releasing factor (LRF), no increase was seen in the plasma luteinizing hormone (LH) in 3 subjects (1 nursing, 2 not nursing) studied in the first 3 wk after delivery. When studied again 6 wk or later after delivery, a normal increase was observed in plasma LH following LRF administration. These studies suggest that the pituitary gland might be temporarily resistant to stimulation by LRF in the early postpartum period.

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Temporary pituitary insensitivity to stimulation by synthetic LRF during the postpartum period

Abstract

ASJC Scopus subject areas

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