Temporary pituitary insensitivity to stimulation by synthetic LRF during the postpartum period

W. J. LeMaire, A. G. Shapiro, F. Riggall, N. S.T. Yang

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Following a subcutaneous injection of 100 μg of synthetic luteinizing hormone releasing factor (LRF), no increase was seen in the plasma luteinizing hormone (LH) in 3 subjects (1 nursing, 2 not nursing) studied in the first 3 wk after delivery. When studied again 6 wk or later after delivery, a normal increase was observed in plasma LH following LRF administration. These studies suggest that the pituitary gland might be temporarily resistant to stimulation by LRF in the early postpartum period.

Original languageEnglish (US)
Pages (from-to)916-918
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume38
Issue number5
DOIs
StatePublished - Jan 1 1974

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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