Temporary Fillers

Kavita Mariwalla, Rhoda S. Narins, Luitgard G. Wiest, Katlein França, Yasser Alqubaisy, Janelle Vega, Mariano Busso, Fredric S. Brandt, Joely Kaufman, Jeremy B. Green, Annelyse C. Ballin, Alex Cazzaniga

Research output: Chapter in Book/Report/Conference proceedingChapter


Microlipoinjection or autologous fat transfer is a three-step process by which innate adipocytes are transferred to replace volume loss associated with normal aging. Common side effects are bruising and edema, which are temporary. Collagen implants were the first injectable implants and remained for decades the mainstay of dermal fillers. With the rise of longer lasting, more versatile and easy-to-use dermal fillers based on hyaluronic acid they increasingly lost significance. Poly-l-lactic acid (PLLA), a synthetic polymer, is biologically inert, biocompatible, and biodegradable, and it initiates neocollagenesis by stimulating a foreign-body reaction. Calcium hydroxyapatite is a semi-permanent filler, consisting of CaHA microspheres in a carrier gel. Currently, hyaluronic acid (HA) fillers are the most popular injectable fillers available for facial contouring and rejuvenation. The FDA-approved HA fillers currently on the market are composed of bacterial derived HA that is cross-linked to improve stability.

Original languageEnglish (US)
Title of host publicationDermatologic Surgery
Subtitle of host publicationStep by Step
Number of pages27
ISBN (Print)9781444330670
StatePublished - Sep 7 2012


  • Adipocyte
  • Autologous fat transfer
  • Calcium hydroxyapatite
  • Collagen
  • Dermal fillers
  • Hyaluronic acid
  • Microlipoinjection
  • Semipermanent dermal filler
  • Tumescent liposuction

ASJC Scopus subject areas

  • Medicine(all)


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