Temporal lobectomy for seizures associated with unilateral schizencephaly

Howard Landy, R. Eugene Ramsay, Cosimo Ajmone-Marsan, Bonnie Levin, Jay Brown, Guillermo Pasarin, Robert Quencer

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Schizencephaly is characterized by unilateral or bilateral cerebral clefts associated with neurologic deficits and epilepsy. Most commonly schizencephaly is attributed to abnormal neuronal migration, and these malformations are well visualized by current neuroimaging techniques. This report describes a patient with unilateral schizencephaly and poorly controlled complex partial seizures who was found to have a temporal lobe seizure focus; anterior temporal lobectomy produced nearly complete control of the seizures. Despite the extensive malformation, relatively restricted resection was of significant benefit. The principles of seizure focus localization and resection are applicable to the management of patients with schizencephaly.

Original languageEnglish
Pages (from-to)477-481
Number of pages5
JournalSurgical Neurology
Volume37
Issue number6
DOIs
StatePublished - Jan 1 1992

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Seizures
Anterior Temporal Lobectomy
Temporal Lobe
Neurologic Manifestations
Neuroimaging
Epilepsy
Schizencephaly

Keywords

  • Epilepsy
  • Neuronal migration
  • Schizencephaly

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Temporal lobectomy for seizures associated with unilateral schizencephaly. / Landy, Howard; Ramsay, R. Eugene; Ajmone-Marsan, Cosimo; Levin, Bonnie; Brown, Jay; Pasarin, Guillermo; Quencer, Robert.

In: Surgical Neurology, Vol. 37, No. 6, 01.01.1992, p. 477-481.

Research output: Contribution to journalArticle

Landy, Howard ; Ramsay, R. Eugene ; Ajmone-Marsan, Cosimo ; Levin, Bonnie ; Brown, Jay ; Pasarin, Guillermo ; Quencer, Robert. / Temporal lobectomy for seizures associated with unilateral schizencephaly. In: Surgical Neurology. 1992 ; Vol. 37, No. 6. pp. 477-481.
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