Technology insight: Applications of tissue engineering and biological substitutes in urology

Anthony Atala

Research output: Contribution to journalReview article

23 Scopus citations

Abstract

Patients suffering from diseased or injured organs may be treated with transplanted organs. However, there is a severe shortage of donor organs, which is worsening yearly owing to the ageing population. Scientists in the field of regenerative medicine and tissue engineering apply the principles of cell transplantation, materials science, and bioengineering to construct biological substitutes that will restore and maintain normal function in diseased and injured tissues. This article reviews recent advances in regenerative medicine and describes applications of biological substitutes that may offer novel therapies for patients with end-stage organ failure.

Original languageEnglish (US)
Pages (from-to)143-149
Number of pages7
JournalNature Clinical Practice Urology
Volume2
Issue number3
DOIs
StatePublished - Mar 1 2005

Keywords

  • Biomaterials
  • Extracellular matrix
  • Therapeutic cloning
  • Tissue engineering

ASJC Scopus subject areas

  • Urology
  • Nephrology

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