Entwicklung einer neuen implantationstechnik zur supraDescemetalen implantation einer lamellären keratoprothese

Translated title of the contribution: Technique for SupraDescemetic implantation of a lamellar keratoprosthesis

Josef Stoiber, V. Fernandez, S. Kaminski, P. Lamar, J. M. Parel

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Background: Implantation of a keratoprosthesis (KPro) or 'synthetic cornea' is the last resort in regaining useful vision in patients with corneal blindness not amenable to conventional corneal transplantation. Complications in these penetrating devices are common and sometimes severe, therefore a non-penetrating, lamellar KPro was developed. Methods: The technique for implantation was developed and tested in an animal model (New Zealand White Rabbits). A paralimbal corneal incision was performed at 85% thickness, followed by preparation of an intracorneal pocket and trephination (3.7 mm) of the anterior lamella. The remaining stroma was removed by blunt dissection. The sDSC was positioned with its central optic part on bare Descemet's membrane (DM) and with its peripheral haptic in deep corneal stroma. The operation was performed in the right eye of 41 rabbits. 25 corneas were clear and healthy, 16 corneas were vascularized at time of surgery. Results: Implantation of the sDSC could be performed successfully in 15 of the first 22 consecutive cases, perforation of DM occurred in 7 eyes. Minor modification of the surgery (reduction of the intraocular pressure via paracentesis) significantly improved the success. In none of the following 19 cases a perforation of DM occurred. Implantation depth was evaluated by histology, showing a bare DM. Conclusion: As the anterior chamber is not altered during sDSC surgery, the complication rate could be less compared to implantation of a penetrating devive.

Translated title of the contributionTechnique for SupraDescemetic implantation of a lamellar keratoprosthesis
Original languageGerman
Pages (from-to)139-142
Number of pages4
JournalSpektrum der Augenheilkunde
Volume18
Issue number3
DOIs
StatePublished - Jan 1 2004

Keywords

  • Artificial cornea
  • Descemet's membrane
  • Keratoprosthesis

ASJC Scopus subject areas

  • Ophthalmology

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