Technetium pyrophosphate muscle scans in inflammatory muscle disease

R. A. Yonker, Ella M. Webster, N. L. Edwards, P. Katz, S. Longley, H. Petterssen, R. S. Panush

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Technetium-99M pyrophosphate (TcPYP) nuclear scans of extremities were performed on 15 patients at 10 minutes and 2 hours after isotope injection. Scans were carried out both to confirm the diagnosis of myositis and to direct subsequent muscle biopsy. Five of six patients with clinical features strongly suggestive of inflammatory muscle disease had positive scans. All muscle biopsies performed at areas of increased isotope uptake showed inflammatory muscle disease. All nine patients not suspected of active inflammatory muscle disease had negative scans. Two of these underwent muscle biopsy with negative results. Our observations suggest that TcPYP muscle scans may be useful both to confirm the clinical suspicion of inflammatory muscle disease and in directing the choice of site for muscle biopsy.

Original languageEnglish (US)
Pages (from-to)267-269
Number of pages3
Issue number4
StatePublished - Aug 1987


  • Inflammatory muscle disease
  • Muscle scans
  • Myositis
  • Scans
  • Technetium-99M pyrophosphate

ASJC Scopus subject areas

  • Rheumatology
  • Pharmacology (medical)


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