Teaching cancer imaging in the era of precision medicine: Looking at the big picture

Christopher N Chin, Ty Subhawong, James Grosso, Jeremy R. Wortman, Lacey J. McIntosh, Ryan Tai, Marta Braschi-Amirfarzan, Patricia Castillo, Francesco Alessandrino

Research output: Contribution to journalShort surveypeer-review

Abstract

The role of imaging in cancer diagnosis and treatment has evolved at the same rapid pace as cancer management. Over the last twenty years, with the advancement of technology, oncology has become a multidisciplinary field that allows for researchers and clinicians not only to create individualized treatment options for cancer patients, but also to evaluate patients’ response to therapy with increasing precision. Familiarity with these concepts is a requisite for current and future radiologists, as cancer imaging studies represent a significant and growing component of any radiology practice, from tertiary cancer centers to community hospitals. In this review we provide the framework to teach cancer imaging in the era of genomic oncology. After reading this article, readers should be able to illustrate the basics cancer genomics, modern cancer genomics, to summarize the types of systemic oncologic therapies available, their patterns of response and their adverse events, to discuss the role of imaging in oncologic clinical trials and the role of tumor response criteria and to display the future directions of oncologic imaging.

Original languageEnglish (US)
Article number100414
JournalEuropean Journal of Radiology Open
Volume9
DOIs
StatePublished - Jan 2022
Externally publishedYes

Keywords

  • Adverse events, clinical trials
  • Checkpoint inhibitors
  • Molecular targeted therapies
  • Oncologic imaging
  • Tumor response criteria

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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