Targets for molecular intervention in multistep pulmonary carcinogenesis

David S. Schrump, Dao Nguyen

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Lung cancers are a leading cause of mortality worldwide, and most of these neoplasms are directly attributable to tobacco abuse. Recent studies have begun to elucidate molecular mechanisms of multistep aero-digestive tract carcinogenesis, revealing novel targets for intervention in lung cancers and their precursor lesions. This review summarizes the molecular biology of lung cancers in relation to the prognosis and treatment of patients with these neoplasms.

Original languageEnglish
Pages (from-to)174-183
Number of pages10
JournalWorld Journal of Surgery
Volume25
Issue number2
DOIs
StatePublished - Apr 26 2001
Externally publishedYes

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Lung Neoplasms
Carcinogenesis
Lung
Tobacco
Gastrointestinal Tract
Molecular Biology
Neoplasms
Mortality
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

Targets for molecular intervention in multistep pulmonary carcinogenesis. / Schrump, David S.; Nguyen, Dao.

In: World Journal of Surgery, Vol. 25, No. 2, 26.04.2001, p. 174-183.

Research output: Contribution to journalArticle

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