Targeting nitric oxide to cancer cells: Cytotoxicity studies of glyco-S- nitrosothiols

Yongchun Hou, Jianqiang Wang, Peter R. Andreana, Guilleherme Cantauria, Srikumar Tarasia, Laura Sharp, Paul G. Braunschweiger, Peng G. Wang

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

Glyco-S-nitrosothiols, fructose-2-SNAP and glucose-2-SNAP, were synthesized and found to be much more cytotoxic than SNAP in killing DU-145 human prostate cancer cells in vitro.

Original languageEnglish (US)
Pages (from-to)2255-2258
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume9
Issue number15
DOIs
StatePublished - Aug 2 1999

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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  • Cite this

    Hou, Y., Wang, J., Andreana, P. R., Cantauria, G., Tarasia, S., Sharp, L., Braunschweiger, P. G., & Wang, P. G. (1999). Targeting nitric oxide to cancer cells: Cytotoxicity studies of glyco-S- nitrosothiols. Bioorganic and Medicinal Chemistry Letters, 9(15), 2255-2258. https://doi.org/10.1016/S0960-894X(99)00363-7