Targeting nitric oxide to cancer cells

Cytotoxicity studies of glyco-S- nitrosothiols

Yongchun Hou, Jianqiang Wang, Peter R. Andreana, Guilleherme Cantauria, Srikumar Tarasia, Laura Sharp, Paul G Braunschweiger, Peng G. Wang

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Glyco-S-nitrosothiols, fructose-2-SNAP and glucose-2-SNAP, were synthesized and found to be much more cytotoxic than SNAP in killing DU-145 human prostate cancer cells in vitro.

Original languageEnglish
Pages (from-to)2255-2258
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume9
Issue number15
DOIs
StatePublished - Aug 2 1999

Fingerprint

S-Nitrosothiols
Cytotoxicity
Prostatic Neoplasms
Nitric Oxide
Cells
Neoplasms
glucose-2-SNAP
fructose-2-SNAP
In Vitro Techniques

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science

Cite this

Hou, Y., Wang, J., Andreana, P. R., Cantauria, G., Tarasia, S., Sharp, L., ... Wang, P. G. (1999). Targeting nitric oxide to cancer cells: Cytotoxicity studies of glyco-S- nitrosothiols. Bioorganic and Medicinal Chemistry Letters, 9(15), 2255-2258. https://doi.org/10.1016/S0960-894X(99)00363-7

Targeting nitric oxide to cancer cells : Cytotoxicity studies of glyco-S- nitrosothiols. / Hou, Yongchun; Wang, Jianqiang; Andreana, Peter R.; Cantauria, Guilleherme; Tarasia, Srikumar; Sharp, Laura; Braunschweiger, Paul G; Wang, Peng G.

In: Bioorganic and Medicinal Chemistry Letters, Vol. 9, No. 15, 02.08.1999, p. 2255-2258.

Research output: Contribution to journalArticle

Hou, Y, Wang, J, Andreana, PR, Cantauria, G, Tarasia, S, Sharp, L, Braunschweiger, PG & Wang, PG 1999, 'Targeting nitric oxide to cancer cells: Cytotoxicity studies of glyco-S- nitrosothiols', Bioorganic and Medicinal Chemistry Letters, vol. 9, no. 15, pp. 2255-2258. https://doi.org/10.1016/S0960-894X(99)00363-7
Hou, Yongchun ; Wang, Jianqiang ; Andreana, Peter R. ; Cantauria, Guilleherme ; Tarasia, Srikumar ; Sharp, Laura ; Braunschweiger, Paul G ; Wang, Peng G. / Targeting nitric oxide to cancer cells : Cytotoxicity studies of glyco-S- nitrosothiols. In: Bioorganic and Medicinal Chemistry Letters. 1999 ; Vol. 9, No. 15. pp. 2255-2258.
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