Abstract
Surgical gamma detection probes (GDPs) have become important in the surgical management of neoplastic disease in the past 20 years. Their history and radiophysics are discussed, with consideration of the overarching issue of tumor-to-background ratio (TBR). GDPs are currently most commonly used in sentinel node applications in a variety of tumors. Whether their role in clinical surgical practice can be extended to other applications will depend on the development of radiolabeled tumor marking agents which have much improved TBR, and parallel developments in oncology research which may overtake this technology.
| Original language | English |
|---|---|
| Pages (from-to) | 286-289 |
| Number of pages | 4 |
| Journal | Journal of Surgical Oncology |
| Volume | 96 |
| Issue number | 4 |
| DOIs | |
| State | Published - Sep 15 2007 |
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Keywords
- Radioimmunoguided surgery
- Sentinel node biopsy
- Tumor-to background ratio
ASJC Scopus subject areas
- Surgery
- Oncology
Cite this
Targeting gold at the end of the rainbow : Surgical gamma probes in the 21st century. / Moffat, Frederick L.
In: Journal of Surgical Oncology, Vol. 96, No. 4, 15.09.2007, p. 286-289.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Targeting gold at the end of the rainbow
T2 - Surgical gamma probes in the 21st century
AU - Moffat, Frederick L
PY - 2007/9/15
Y1 - 2007/9/15
N2 - Surgical gamma detection probes (GDPs) have become important in the surgical management of neoplastic disease in the past 20 years. Their history and radiophysics are discussed, with consideration of the overarching issue of tumor-to-background ratio (TBR). GDPs are currently most commonly used in sentinel node applications in a variety of tumors. Whether their role in clinical surgical practice can be extended to other applications will depend on the development of radiolabeled tumor marking agents which have much improved TBR, and parallel developments in oncology research which may overtake this technology.
AB - Surgical gamma detection probes (GDPs) have become important in the surgical management of neoplastic disease in the past 20 years. Their history and radiophysics are discussed, with consideration of the overarching issue of tumor-to-background ratio (TBR). GDPs are currently most commonly used in sentinel node applications in a variety of tumors. Whether their role in clinical surgical practice can be extended to other applications will depend on the development of radiolabeled tumor marking agents which have much improved TBR, and parallel developments in oncology research which may overtake this technology.
KW - Radioimmunoguided surgery
KW - Sentinel node biopsy
KW - Tumor-to background ratio
UR - http://www.scopus.com/inward/record.url?scp=34848850435&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34848850435&partnerID=8YFLogxK
U2 - 10.1002/jso.20861
DO - 10.1002/jso.20861
M3 - Article
C2 - 17726662
AN - SCOPUS:34848850435
VL - 96
SP - 286
EP - 289
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
SN - 0022-4790
IS - 4
ER -