Targeting gold at the end of the rainbow: Surgical gamma probes in the 21st century

Frederick L. Moffat

doi:10.1002/jso.20861

Targeting gold at the end of the rainbow: Surgical gamma probes in the 21st century

Frederick L. Moffat

Surgery

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Surgical gamma detection probes (GDPs) have become important in the surgical management of neoplastic disease in the past 20 years. Their history and radiophysics are discussed, with consideration of the overarching issue of tumor-to-background ratio (TBR). GDPs are currently most commonly used in sentinel node applications in a variety of tumors. Whether their role in clinical surgical practice can be extended to other applications will depend on the development of radiolabeled tumor marking agents which have much improved TBR, and parallel developments in oncology research which may overtake this technology.

Original language	English (US)
Pages (from-to)	286-289
Number of pages	4
Journal	Journal of surgical oncology
Volume	96
Issue number	4
DOIs	https://doi.org/10.1002/jso.20861
State	Published - Sep 15 2007

Keywords

Radioimmunoguided surgery
Sentinel node biopsy
Tumor-to background ratio

ASJC Scopus subject areas

Surgery
Oncology

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10.1002/jso.20861

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abstract = "Surgical gamma detection probes (GDPs) have become important in the surgical management of neoplastic disease in the past 20 years. Their history and radiophysics are discussed, with consideration of the overarching issue of tumor-to-background ratio (TBR). GDPs are currently most commonly used in sentinel node applications in a variety of tumors. Whether their role in clinical surgical practice can be extended to other applications will depend on the development of radiolabeled tumor marking agents which have much improved TBR, and parallel developments in oncology research which may overtake this technology.",

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AB - Surgical gamma detection probes (GDPs) have become important in the surgical management of neoplastic disease in the past 20 years. Their history and radiophysics are discussed, with consideration of the overarching issue of tumor-to-background ratio (TBR). GDPs are currently most commonly used in sentinel node applications in a variety of tumors. Whether their role in clinical surgical practice can be extended to other applications will depend on the development of radiolabeled tumor marking agents which have much improved TBR, and parallel developments in oncology research which may overtake this technology.

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